1-(1-Naphthyl)piperazine - 98%, high purity , CAS No.57536-86-4, Agonist of 5-HT 1A receptor;Agonist of 5-HT 1B receptor;Agonist of 5-HT 1D receptor;Antagonist of 5-ht 1e receptor;Antagonist of 5-HT 1F receptor;Antagonist of 5-HT 2B receptor;Agonist of 5-HT 6 receptor;Agonist of 5-HT 7 receptor
1-(1-Naphthyl)piperazine - 98%, high purity , CAS No.57536-86-4, Agonist of 5-HT 1A receptor;Agonist of 5-HT 1B receptor;Agonist of 5-HT 1D receptor;Antagonist of 5-ht 1e receptor;Antagonist of 5-HT 1F receptor;Antagonist of 5-HT 2B receptor;Agonist of 5-HT 6 receptor;Agonist of 5-HT 7 receptor
Agonist of 5-HT 1A receptor;Agonist of 5-HT 1B receptor;Agonist of 5-HT 1D receptor;Antagonist of 5-ht 1e receptor;Antagonist of 5-HT 1F receptor;Antagonist of 5-HT 2B receptor;Agonist of 5-HT 6 receptor;Agonist of 5-HT 7 receptor
Product Description
Product description:
1-(1-Naphthyl)piperazine is the hydrochloride salt preparation of 1-(1-Naphthyl)piperazine, a small molecule modulator of the 5-HT (serotonin) receptors with mixed activity. 1-(1-Naphthyl)piperazine demonstrates agonist activity at the 5-HT|1A|receptor and antagonist activity at the 5-HT|2A/2C|receptor. Blockade of the peripheral vascular pressor response to 5-HT and attenuation of the stimulus properties of 2,5-dimethoxy-4-methyl-amphetamine, both associated with the 5-HT2 receptor, are correlated to the 5-HT2 antagonism produced by 1-(1-Naphthyl)piperazine. The agonism of 5-HT|1A|produced by 1-(1-Naphthyl)piperazine is correlated to a reduction in 5-HT turnover and an increase in serum corticosterone. 1-(1-Naphthyl)piperazine is an inhibitor of SR-2A and an activator of SR-1A.