1,2-Dibromoethane-1-sulfonyl fluoride - 90%, high purity , CAS No.103020-97-9

Item Number

D486510

Grouped product items
SKU	Size	Availability	Price
D486510-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$144.90
D486510-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$239.90
D486510-250mg	250mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$497.90
D486510-1g	1g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,789.90

Basic Description

Specifications & Purity	≥90%
Product Description	1,2-Dibromoethane-1-sulfonyl fluoride (DESF) is a bench-stable precursor to 1-bromoethene-1-sulfonyl fluoride (BESF), a new and robust connective hub for the Sulfur (VI) fluoride exchange (SuFEx) click reaction. BESF offers similar routes as ethenesulfonyl fluoride (ESF, cat#746959) but with additional reactivity due to the embedded bromo group.Treatment of DESF with triethylamine generates BESF in situ, which has been used to synthesize diverse and unprecented sulfonyl fluorides in good-to-excellent yields. As the resulting molecules possess sulfonyl fluoride handles, further SuFEx reactions are also possible. DESF adds another useful tool for conjugation strategies in chemical biology and organic and polymer synthesis.

IUPAC Name

1,2-dibromoethanesulfonyl fluoride

INCHI

InChI=1S/C2H3Br2FO2S/c3-1-2(4)8(5,6)7/h2H,1H2

InChi Key

NIJDNCLEFCJVRL-UHFFFAOYSA-N

Canonical SMILES

C(C(S(=O)(=O)F)Br)Br

Isomeric SMILES

C(C(S(=O)(=O)F)Br)Br

PubChem CID

Molecular Weight

269.92

Flash Point(°F)

Not applicable

Flash Point(°C)

Not applicable

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation
Precautionary Statements	P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P302+P352:IF ON SKIN: wash with plenty of water.

References

1. Jing Leng, Hua-Li Qin,. (2018-04-17) 1-Bromoethene-1-sulfonyl fluoride (1-Br-ESF), a new SuFEx clickable reagent, and its application for regioselective construction of 5-sulfonylfluoro isoxazoles.. Chemical communications (Cambridge, England), 54 ((35)): ( 4477-4480 ). [PMID:29658035]

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Basic Description