1,4-Dideoxy-1,4-imino-D-mannitol hydrochloride - ≥95%, high purity , CAS No.114976-76-0

  • ≥95%
Item Number
D352146
Grouped product items
SKUSizeAvailabilityPrice Qty
D352146-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$332.90

Basic Description

Synonyms114976-76-0 | 1,4-DIDEOXY-1,4-IMINO-D-MANNITOL HYDROCHLORIDE | 1,4-Dideoxy-1,4-imino-D-mannitol, Hydrochloride | (2R,3S,4R)-2-((S)-1,2-Dihydroxyethyl)pyrrolidine-3,4-diol hydrochloride | (2R,3S,4R)-2-[(1S)-1,2-dihydroxyethyl]pyrrolidine-3,4-diol;hydrochloride | SCH
Specifications & Purity≥95%
Storage TempStore at 2-8°C
Shipped InWet ice
Product Description

A competitive inhibitor of glycosidase. It is also a glycoprotein mannosidase inhibitor - inhibiting jack bean, and to a lesser extent lysosomal alpha-mannosidase. An azofuranose mannose analog, and is structurally related to swainsonine.

Associated Targets(Human)

A498 42825 Activities

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ACHN 49357 Activities

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CAKI-1 44928 Activities

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CCRF-CEM 65223 Activities

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COLO 205 50209 Activities

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DU-145 51482 Activities

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HL-60 67320 Activities

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HT-29 80576 Activities

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KM12 47707 Activities

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M14 47487 Activities

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MCF7 126967 Activities

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MOLT-4 49676 Activities

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OVCAR-3 48710 Activities

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OVCAR-4 44535 Activities

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OVCAR-5 45555 Activities

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OVCAR-8 47708 Activities

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PC-3 62116 Activities

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RPMI-8226 44974 Activities

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RXF 393 41971 Activities

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SF-295 48000 Activities

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SK-MEL-28 48833 Activities

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SK-MEL-5 47095 Activities

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SK-OV-3 52876 Activities

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SN12C 47755 Activities

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SNB-19 46794 Activities

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TK-10 45540 Activities

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U-251 51189 Activities

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UACC-257 46019 Activities

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UACC-62 47335 Activities

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UO-31 46270 Activities

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786-0 47912 Activities

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A549 127892 Activities

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EKVX 44102 Activities

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NCI-H322M 45589 Activities

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HCC 2998 41480 Activities

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HCT-116 91556 Activities

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HOP-92 41141 Activities

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Hs-578T 29457 Activities

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NCI-H460 60772 Activities

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SF-268 49410 Activities

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IGROV-1 47897 Activities

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HOP-62 47048 Activities

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MDA-MB-435 38290 Activities

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MDA-N 28205 Activities

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Malme-3M 44254 Activities

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SNB-75 44215 Activities

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NCI-H23 49055 Activities

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NCI-H522 44358 Activities

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BT-549 31254 Activities

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SF-539 44845 Activities

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Associated Targets(non-human)

Names and Identifiers

IUPAC Name (2R,3S,4R)-2-[(1S)-1,2-dihydroxyethyl]pyrrolidine-3,4-diol;hydrochloride
INCHI InChI=1S/C6H13NO4.ClH/c8-2-4(10)5-6(11)3(9)1-7-5;/h3-11H,1-2H2;1H/t3-,4-,5-,6-;/m1./s1
InChi Key IFRNNJQXHHLGKS-MVNLRXSJSA-N
Canonical SMILES C1C(C(C(N1)C(CO)O)O)O.Cl
Isomeric SMILES C1[C@H]([C@H]([C@H](N1)[C@@H](CO)O)O)O.Cl
WGK Germany 3
PubChem CID 11194983
Molecular Weight 199.63

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySoluble in water.
Boil Point(°C)448.6° C at 760 mmHg (Predicted)
Melt Point(°C)147-148° C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 3

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