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1-[5-(5,6-dimethoxy-1H-1,3-benzodiazol-1-yl)-3-{[2-(trifluoromethyl)phenyl]methoxy}thiophen-2-yl]ethen-1-amine , CAS No.D609074, Inhibitor of polo like kinase 1

1-[5-(5,6-dimethoxy-1H-1,3-benzodiazol-1-yl)-3-{[2-(trifluoromethyl)phenyl]methoxy}thiophen-2-yl]ethen-1-amine , CAS No.D609074, Inhibitor of polo like kinase 1

Item Number

D609074

Grouped product items
SKU	Size	Availability	Price	Qty
D609074-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,400.90
D609074-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,000.90

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Basic Description

Synonyms	compound 2
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of polo like kinase 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

IUPAC Name	1-[5-(5,6-dimethoxy-1H-1,3-benzodiazol-1-yl)-3-{[2-(trifluoromethyl)phenyl]methoxy}thiophen-2-yl]ethen-1-amine
INCHI	InChI=1S/C23H20F3N3O3S/c1-13(27)22-20(32-11-14-6-4-5-7-15(14)23(24,25)26)10-21(33-22)29-12-28-16-8-18(30-2)19(31-3)9-17(16)29/h4-10,12H,1,11,27H2,2-3H3
InChi Key	SYQIMXCJFHFKLG-UHFFFAOYSA-N
Canonical SMILES	COc1cc2c(cc1OC)ncn2c1cc(c(s1)C(=C)N)OCc1ccccc1C(F)(F)F
Isomeric SMILES	COC1=C(C=C2C(=C1)N=CN2C3=CC(=C(S3)C(=C)N)OCC4=CC=CC=C4C(F)(F)F)OC
PubChem CID	91827384

PubChem CID	91827384

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1. Emmitte KA, Andrews CW, Badiang JG, Davis-Ward RG, Dickson HD, Drewry DH, Emerson HK, Epperly AH, Hassler DF, Knick VB et al.. (2009) Discovery of thiophene inhibitors of polo-like kinase.. Bioorg Med Chem Lett, 19 (3): (1018-21). [PMID:19097784]

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