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1,5,7-Triazabicyclo[4.4.0]dec-5-ene - ≥90%, high purity , CAS No.5807-14-7

≥90%

CAS#: 5807-14-7
Formula: C₇H₁₃N₃
Molecular Weight: 139.20
Beilstein Registry Number: 3242
MDL number: MFCD00043003
PubChem CID: 79873

Item Number

T473437

Grouped product items
SKU	Size	Availability	Price	Qty
T473437-1g	1g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$20.90
T473437-5g	5g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$49.90

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Organic base

Basic Description

Specifications & Purity	≥90%
Storage Temp	Argon charged
Shipped In	Normal
Product Description	1,5,7-Triazabicyclo[4.4.0]dec-5-ene, a bicyclic guanidine base, has been found to be an excellent catalyst for Michael and Michael-type reactions. It forms 1:1 complex with lasalocid acid and crystal structure of the complex has been studied by X-ray diffraction, FT-IR spectroscopy and1H NMR.1,5,7-Triazabicyclo[4.4.0]dec-5-ene may be used as organocatalyst for aminolysis of esters. It may be used as catalyst for direct addition of P(O)-H bonds (dialkyl phosphites and diphenyl phosphonite) across various activated alkenes. Polymer supported 1,5,7-triazabicyclo[4.4.0]dec-5-ene (PTBD) was used as a base and a reagent scavenger for the synthesis of aryl ethers from phenols and alkyl or aryl halides.

Names and Identifiers

IUPAC Name	3,4,6,7,8,9-hexahydro-2H-pyrimido[1,2-a]pyrimidine
INCHI	InChI=1S/C7H13N3/c1-3-8-7-9-4-2-6-10(7)5-1/h1-6H2,(H,8,9)
InChi Key	FVKFHMNJTHKMRX-UHFFFAOYSA-N
Canonical SMILES	C1CNC2=NCCCN2C1
Isomeric SMILES	C1CNC2=NCCCN2C1
WGK Germany	3
PubChem CID	79873
Molecular Weight	139.20
Beilstein	3242
Reaxy-Rn	3242

Certificates

Certificate of Analysis(COA)

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3 results found

Lot Number	Certificate Type	Date	Item
H2408555	Certificate of Analysis	Aug 15, 2024	T473437
H2408556	Certificate of Analysis	Aug 15, 2024	T473437
H2408557	Certificate of Analysis	Aug 15, 2024	T473437

Solubility

acetonitrile: soluble; ethanol: soluble; organic solvents: soluble; water: soluble

Sensitivity

Moisture & air sensitive

Melt Point(°C)

130 °C

Safety and Hazards(GHS)

Pictogram(s)	GHS05
Signal	Danger
Hazard Statements	H314:Causes severe skin burns and eye damage H318:Causes serious eye damage
Precautionary Statements	P280:Wear protective gloves/protective clothing/eye protection/face protection. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P363:Wash contaminated clothing before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P317:Get emergency medical help. P302+P361+P354:IF ON SKIN: Take off Immediately all contaminated clothing. Immediately rinse with water for several minutes. P316:Get emergency medical help immediately.
WGK Germany	3
Reaxy-Rn	3242

References

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2. Shouru Zhang,Zhongxue Fu,Jinlai Wei,Jinbao Guo,Maoxi Liu,Kunli Du. (2014-12-05) Peroxiredoxin 2 is involved in vasculogenic mimicry formation by targeting VEGFR2 activation in colorectal cancer.. Medical oncology (Northwood, London, England), 32 ((1)): (414-414). [PMID:25471788]
3. Xiang Zeng,Xue-Cheng Qiu,Yuan-Huan Ma,Jing-Jing Duan,Yuan-Feng Chen,Huai-Yu Gu,Jun-Mei Wang,Eng-Ang Ling,Jin-Lang Wu,Wutian Wu,Yuan-Shan Zeng. (2015-04-22) Integration of donor mesenchymal stem cell-derived neuron-like cells into host neural network after rat spinal cord transection.. Biomaterials, 53 (184-201). [PMID:25890718]
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5. Jinfeng Wang,Xin Zhang,Lili Wang,Zhaogang Dong,Lutao Du,Yongmei Yang,Yuan Guo,Chuanxin Wang. (2015-05-16) Downregulation of urinary cell-free microRNA-214 as a diagnostic and prognostic biomarker in bladder cancer.. Journal of surgical oncology, 111 ((8)): (992-999). [PMID:25975233]
6. Lei Li,Yunpeng Li,Hongkun Jiang. (2015-07-26) Neurotrophine-3 may contribute to neuronal differentiation of mesenchymal stem cells through the activation of the bone morphogenetic protein pathway.. Cellular & molecular biology letters, 20 ((3)): (385-403). [PMID:26208387]
7. Rong Sun,Xiao-Jiao Du,Chun-Yang Sun,Song Shen,Yang Liu,Xian-Zhu Yang,Yan Bao,Yan-Hua Zhu,Jun Wang. (2015-07-30) A block copolymer of zwitterionic polyphosphoester and polylactic acid for drug delivery.. Biomaterials science, 3 ((7)): (1105-1113). [PMID:26221944]
8. Xin Zhao,Yuan-Qi Shi,Cai-Chuan Yan,Pan-feng Feng,Xue Wang,Rui Zhang,Xiao Zhang,Bao-Xin Li. (2014-11-15) Up-regulation of miR-21 and miR-23a Contributes to As2 O3 -induced hERG Channel Deficiency.. Basic & clinical pharmacology & toxicology, 116 ((6)): (516-523). [PMID:25395240]
9. Jinfeng Wang,Xin Zhang,Lili Wang,Yongmei Yang,Zhaogang Dong,Haiyan Wang,Lutao Du,Chuanxin Wang. (2015-02-24) MicroRNA-214 suppresses oncogenesis and exerts impact on prognosis by targeting PDRG1 in bladder cancer.. PloS one, 10 ((2)): (e0118086-e0118086). [PMID:25706919]
10. Hao Zhang,Yan Ma,Shenghua Zhang,Hong Liu,Hongwei He,Naren Li,Yuyan Gong,Shuangshuang Zhao,Jian-Dong Jiang,Rong-Guang Shao. (2015-05-13) Involvement of Ras GTPase-activating protein SH3 domain-binding protein 1 in the epithelial-to-mesenchymal transition-induced metastasis of breast cancer cells via the Smad signaling pathway.. Oncotarget, 6 ((19)): (17039-17053). [PMID:25962958]

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