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1,5-Anhydro-D-mannitol , CAS No.492-93-3
a gluconeogenesis inhibitor
Basic Description Synonyms 1,5-Anhydromannitol; 1-deoxy-alpha-D-mannose; 1-deoxy-D-mannose; 1-deoxy-mannose | AH2 | UNII-6V415COZ8I | CS-0204027 | MPCAJMNYNOGXPB-KVTDHHQDSA-N | (-)-(2R,3S,4R,5R)-2-hydroxymethyl-tetrahydro-pyran-3,4,5-triol | 1,5-Anhydromannitol | 1,5-Anhydro-mannit Storage Temp Store at -20°C Shipped In Ice chest + Ice pads Product Description 1,5-Anhydro-D-mannitol is a carbohydrate metabolism regulator that has been shown to inhibit gluconeogenesis from lactate plus pyruvate and from substrates that enter the gluconeogenic pathway as triose phosphate.
Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References
Names and Identifiers IUPAC Name (2R,3S,4R,5R)-2-(hydroxymethyl)oxane-3,4,5-triol INCHI InChI=1S/C6H12O5/c7-1-4-6(10)5(9)3(8)2-11-4/h3-10H,1-2H2/t3-,4-,5-,6-/m1/s1 InChi Key MPCAJMNYNOGXPB-KVTDHHQDSA-N Canonical SMILES C1C(C(C(C(O1)CO)O)O)O Isomeric SMILES C1[C@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O PubChem CID 445184 Molecular Weight 164.16
Chemical and Physical Properties Solubility Soluble in methanol, and water. Refractive Index n20D1.58 (Predicted) Boil Point(°C) 376.75° C at 760 mmHg (Predicted) Melt Point(°C) 156-157° C
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