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1,9-Dideoxyforskolin - ≥95%, high purity , CAS No.64657-18-7

  • ≥95%
Item Number
D329533
Grouped product items
SKUSizeAvailabilityPrice Qty
D329533-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$93.90
D329533-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$308.90
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Discover 1,9-Dideoxyforskolin by Aladdin Scientific in ≥95% for only $93.90. Available - in Ligands at Aladdin Scientific. a Forskolin analog that does not activate adenylate cyclase Tags: VRAC Channel blocker.

View related series
VRAC Channel blocker

Basic Description

Synonyms1,9-DIDEOXYFORSKOLIN|64657-18-7|OAW710HWIX|CHEBI:50295|(3R,4aS,5S,6S,6aS,10aS,10bR)-3-ethenyl-6-hydroxy-3,4a,7,7,10a-pentamethyl-1-oxododecahydro-1H-benzo[f]chromen-5-yl acetate|[(3R,4aS,5S,6S,6aS,10aS,10bR)-3-ethenyl-6-hydroxy-3,4a,7,7,10a-pentamethyl-1-
Specifications & Purity≥95%
SourceColeus forskohlii
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

1,9-Dideoxyforskolin is a derivative of Forskolin which unlike the parent compound is incapable of activating adenylate cyclase. Forskolin-induced stimulation of adenylate cyclase and increased cAMP levels is employed to study the modulation of ion channels and cAMP-dependent second messenger systems, and 1,9-Dideoxyforskolin serves as a negative control for cAMP-related Forskolin inductions. 1,9-Dideoxyforskolin mimics some activity of Forskolin, demonstrating alteration of K|+|channel activity, reversal of doxorubicin resistance in multidrug resistant sarcoma cells, protection against TNF-α-mediated cytotoxicity, and desensitization at GABA|A|receptors.

Product Properties

pKapKa: 13.76 (Predicted)

Names and Identifiers

IUPAC Name [(3R,4aS,5S,6S,6aS,10aS,10bR)-3-ethenyl-6-hydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-2,5,6,6a,8,9,10,10b-octahydrobenzo[f]chromen-5-yl] acetate
INCHI InChI=1S/C22H34O5/c1-8-20(5)12-14(24)16-21(6)11-9-10-19(3,4)17(21)15(25)18(26-13(2)23)22(16,7)27-20/h8,15-18,25H,1,9-12H2,2-7H3/t15-,16+,17-,18-,20-,21+,22-/m0/s1
InChi Key ZKZMDXUDDJYAIB-SUCLLAFCSA-N
Canonical SMILES CC(=O)OC1C(C2C(CCCC2(C3C1(OC(CC3=O)(C)C=C)C)C)(C)C)O
Isomeric SMILES CC(=O)O[C@H]1[C@H]([C@@H]2[C@](CCCC2(C)C)([C@@H]3[C@@]1(O[C@@](CC3=O)(C)C=C)C)C)O
WGK Germany 3
PubChem CID 107948
Molecular Weight 378.5
Beilstein 5304980

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySoluble in methanol (28 mg/mL), DMSO (3 mg/mL), and ethanol (6.6 mg/mL). Insoluble in dilute aqueous acid and base.
Refractive Indexn20D1.52 (Predicted)
Specific Rotation[α]α26/D +93.6°, c = 6.12 in chloroform (lit.)
Boil Point(°C)~455° C at 760 mmHg (Predicted)
Melt Point(°C)162-163° C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H312:Harmful in contact with skin

Precautionary Statements

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P501:Dispose of contents/container to ...

P362+P364:Take off contaminated clothing and wash it before reuse.

P317:Get emergency medical help.

WGK Germany 3

Related Documents

 SDS

 Specification Sheet

Solution Calculators

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