The store will not work correctly when cookies are disabled.
JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.
1-Isopropyl-1,2,3-benzotriazole-5-carboxylic acid - 97%, high purity , CAS No.306935-41-1, Agonist of HCA 3 receptor
Selective agonist for the GPR109B (HM74) receptor. Antilipolytic
Basic Description Synonyms 306935-41-1|ibc 293|1-isopropyl-1h-1,2,3-benzotriazole-5-carboxylic acid|1-propan-2-ylbenzotriazole-5-carboxylic acid|1-isopropyl-1h-benzo[d][1,2,3]triazole-5-carboxylic acid|1-Isopropyl-1,2,3-benzotriazole-5-carboxylic acid|IBC-293|1H-Benzotriazole-5-car Specifications & Purity Moligand™, ≥97% Biochemical and Physiological Mechanisms Highly selective agonist for GPR109B (HM74), human orphan G-protein-coupled receptor expressed in adipocytes. Selective for GPR109B over niacin receptor GPR109A (HM74A); EC50values are 400 nM and > 1μM respectively. Inhibits isoproterenol-stimulated lipol Storage Temp Room temperature Shipped In Normal Grade Moligand™ Action Type AGONIST Mechanism of action Agonist of HCA 3 receptor
Names and Identifiers IUPAC Name 1-propan-2-ylbenzotriazole-5-carboxylic acid INCHI InChI=1S/C10H11N3O2/c1-6(2)13-9-4-3-7(10(14)15)5-8(9)11-12-13/h3-6H,1-2H3,(H,14,15) InChi Key RUTVRAJKELSHCC-UHFFFAOYSA-N Canonical SMILES CC(C)N1C2=C(C=C(C=C2)C(=O)O)N=N1 Isomeric SMILES CC(C)N1C2=C(C=C(C=C2)C(=O)O)N=N1 PubChem CID 2736690 Molecular Weight 205.2
Chemical and Physical Properties Solubility Solvent:DMSO, Max Conc. mg/mL: 20.52, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 20.52, Max Conc. mM: 100
Safety and Hazards(GHS) Pictogram(s) GHS07 Signal Warning Hazard Statements H315: Causes skin irritation
H319: Causes serious eye irritation
H335: May cause respiratory irritation
Precautionary Statements P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352: IF ON SKIN: wash with plenty of water.
P321: Specific treatment (see ... on this label).
P405: Store locked up.
P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P304+P340: IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P403+P233: Store in a well-ventilated place. Keep container tightly closed.
P362+P364: Take off contaminated clothing and wash it before reuse.
P264+P265: Wash hands [and …] thoroughly after handling. Do not touch eyes.
P337+P317: If eye irritation persists: Get medical help.
P332+P317: If skin irritation occurs: Get medical help.
P319: Get medical help if you feel unwell.
Solution Calculators Molarity Calculator Determine the necessary mass, volume, or concentration for preparing a solution.
Dilution Calculator Determine the dilution needed to prepare a stock solution.
Reconstitution Calculator
F2310325