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11-Ethyl Camptothecin , CAS No.185807-29-8
a substituted Topo I inhibitor
Basic Description
Synonyms | 11-Ethyl Camptothecin | 185807-29-8 | (19S)-6,19-diethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione | (4S)-4,8-Diethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Product Description | 11-Ethyl Camptothecin is an anti-tumor, substituted, Camptothecin derivative. 11-Ethyl Camptothecin is a Topo I (topoisomerase 1) inhibitor. |
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Names and Identifiers
IUPAC Name | (19S)-6,19-diethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione |
INCHI | InChI=1S/C22H20N2O4/c1-3-12-5-6-13-8-14-10-24-18(19(14)23-17(13)7-12)9-16-15(20(24)25)11-28-21(26)22(16,27)4-2/h5-9,27H,3-4,10-11H2,1-2H3/t22-/m0/s1 |
InChi Key | SGXXQRSXMWIURP-QFIPXVFZSA-N |
Canonical SMILES | CCC1=CC2=NC3=C(CN4C3=CC5=C(C4=O)COC(=O)C5(CC)O)C=C2C=C1 |
Isomeric SMILES | CCC1=CC2=NC3=C(CN4C3=CC5=C(C4=O)COC(=O)[C@@]5(CC)O)C=C2C=C1 |
PubChem CID | 29979717 |
Molecular Weight | 376.41 |
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