13,14-dihydro-15-keto Prostaglandin D₂ - A solution in methyl acetate, high purity , CAS No.59894-07-4, Agonist of DP 2 receptor

Item Number

D345919

Grouped product items
SKU	Size	Availability	Price	Qty
D345919-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$199.90
D345919-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$902.90

a selective DP2 receptor agonist

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Basic Description

Synonyms	13,14-Dihydro-15-keto-pgd2\|59894-07-4\|13,14-Dihydro-15-ketoprostaglandin D2\|13,14-Dihydro-15-keto-prostaglandin D2\|(Z)-7-[(1R,2R,5S)-5-hydroxy-3-oxo-2-(3-oxooctyl)cyclopentyl]hept-5-enoic acid\|dhk-PGD2\|13,14-DIHYDRO-15-KETO PROSTAGLANDIN D2\|11,15-dioxo-9S
Specifications & Purity	A solution in methyl acetate
Storage Temp	Store at -80°C
Shipped In	Ice chest + Ice pads
Action Type	AGONIST
Mechanism of action	Agonist of DP 2 receptor
Product Description	13,14-dihydro-15-keto Prostaglandin D\|2\|is a metabolite of PGD\|2\|which is formed through the 15-hydroxy PGDH pathway. It has been recently identified as a selective agonist for the DP\|2\|receptor. Additionally, 13,14-dihydro-15-keto Prostaglandin D\|2\|has been shown to inhibit ion flux in canine colonic mucosa preparation.

Names and Identifiers

IUPAC Name	(Z)-7-[(1R,2R,5S)-5-hydroxy-3-oxo-2-(3-oxooctyl)cyclopentyl]hept-5-enoic acid
INCHI	InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,16-18,22H,2-3,5-6,8-14H2,1H3,(H,24,25)/b7-4-/t16-,17-,18+/m1/s1
InChi Key	VSRXYLYXIXYEST-KZTWKYQFSA-N
Canonical SMILES	CCCCCC(=O)CCC1C(C(CC1=O)O)CC=CCCCC(=O)O
Isomeric SMILES	CCCCCC(=O)CC[C@@H]1[C@H]([C@H](CC1=O)O)C/C=C\CCCC(=O)O
Alternate CAS	59894-07-4
PubChem CID	5283036
MeSH Entry Terms	13,14-dihydro-15-keto-PGD2;13,14-dihydro-15-keto-prostaglandin D2;13,14-dihydro-15-ketoprostaglandin D2
Molecular Weight	352.47

Solubility

Soluble in ethanol (30 mg/ml), DMSO (30 mg/ml), DMF (30 mg/ml), and PBS (pH 7.2) (~2.5 mg/ml).

Refractive Index

n20D1.50 (Predicted)

Boil Point(°C)

57° C (Predicted)

Solution Calculators

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Basic Description