Contains four deuterium atoms at the 3, 3', 4, and 4' positions. Intended for use as an internal standard for the quantification of 13,14-dh-15-k PGE1 by GC- or LC-mass spectrometry. A metabolite of PGE1 with much reduced biological activity. Steady state plasma concentrations are about 10 pg/ml. A weak inhibitor of ADP-induced platelet aggregation in human PRP and washed platelets with IC|50|values of 54 and 200 µM.
