Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
SKU | Size | Availability | Price | Qty |
---|---|---|---|---|
D356084-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $235.90 | |
D356084-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,243.90 |
a metabolite of PGF2α shown to bind bovine acetylcholine esterase
Synonyms | 13,14-Dihydro-15-keto-pgf2alpha|Dhk-pgf2alpha|27376-76-7|PGFM|13,14-DIHYDRO-15-KETO PROSTAGLANDIN F2ALPHA|15-Keto-13,14-dihydro-pgf2alpha|13,14-Dihydro-15-oxoprostaglandin F|13,14-Dihydro-15-ketoprostaglandin F2alpha|15-Keto-13,14-dihydroprostaglandin F2a |
---|---|
Specifications & Purity | A solution in methyl acetate,≥95% |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Action Type | AGONIST |
Mechanism of action | Agonist of DP 2 receptor |
Product Description | 13,14-Dihydro-15-keto-prostaglandin F2α is the first substantially accumulating metabolite of PGF2α , that is formed from 15-keto-PGF2α via the 15-hydroxy prostaglandin dehydrogenase pathway. This product has been used to measure the rate of|in vivo|production of PGF2α, and has been shown to covalently bind to bovine acetylcholine esterase. |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
IUPAC Name | (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-(3-oxooctyl)cyclopentyl]hept-5-enoic acid |
---|---|
INCHI | InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,16-19,22-23H,2-3,5-6,8-14H2,1H3,(H,24,25)/b7-4-/t16-,17-,18+,19-/m1/s1 |
InChi Key | VKTIONYPMSCHQI-XAGFEHLVSA-N |
Canonical SMILES | CCCCCC(=O)CCC1C(CC(C1CC=CCCCC(=O)O)O)O |
Isomeric SMILES | CCCCCC(=O)CC[C@H]1[C@@H](C[C@@H]([C@@H]1C/C=C\CCCC(=O)O)O)O |
PubChem CID | 5283039 |
Molecular Weight | 354.48 |
PubChem CID | 5283039 |
---|---|
CAS Registry No. | 27376-76-7 |
ChEBI | CHEBI:63976 |
GPCRdb Ligand | 13,14-dihydro-15-keto-PGF2α |
Enter Lot Number to search for COA:
Boil Point(°C) | 57° C |
---|
Pictogram(s) | GHS07 |
---|---|
Signal | Warning |
Hazard Statements | H302:Harmful if swallowed H312:Harmful in contact with skin H332:Harmful if inhaled |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help. P317:Get emergency medical help. |