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187-1, N-WASP inhibitor TFA, CAS No.380488-27-7(free)

  • ≥98%
Features and benefitsView More
    Item Number
    N287721
    Grouped product items
    SKUSizeAvailabilityPrice Qty
    N287721-1mg
    1mg
    Available within 8-12 weeks(?)
    Production requires sourcing of materials. We appreciate your patience and understanding.
    $216.90
    N287721-5mg
    5mg
    Available within 8-12 weeks(?)
    Production requires sourcing of materials. We appreciate your patience and understanding.
    $349.90
    N287721-10mg
    10mg
    Available within 8-12 weeks(?)
    Production requires sourcing of materials. We appreciate your patience and understanding.
    $599.90
    N287721-25mg
    25mg
    Available within 8-12 weeks(?)
    Production requires sourcing of materials. We appreciate your patience and understanding.
    $1,199.90

    N-WASP inhibitor; inhibits actin assembly

    Basic Description

    Product Name187-1, N-WASP inhibitor TFA, CAS No.380488-27-7(free)
    Product Description

    187-1, N-WASP inhibitor TFA, a 14-aa cyclic peptide, is an allosteric neural Wiskott-Aldrich syndrome protein (N-WASP) inhibitor. 187-1, N-WASP inhibitor TFA potently inhibits actin assembly induced by phosphatidylinositol 4,5-bisphosphate (PIP2) with an IC50 of 2 μM. 187-1, N-WASP inhibitor TFA prevents the activation of Arp2/3 complex by N-WASP by stabilizing the autoinhibited state of the protein.

    Specifications & Purity≥98%
    Biochemical and Physiological MechanismsInhibits neural Wiskott-Aldrich syndrome protein (N-WASP) by stabilizing the autoinhibited state of the protein. Blocks phosphatidylinositol 4,5-bisphosphate (PIP2)-stimulated actin assembly (IC50~ 2μM) but does not directly inhibit actin polymerization.
    SequenceKFPFFPQ KFPFFPQ(Modifications: Phe-2 = D-Phe, Pro-3 = D-Pro, Phe-4 = D-Phe, Pro-6 = D-Pro, Cyclized)

    AI Insight

    Product Specifications

    Storage TempProtected from light,Store at -20°C,Argon charged,Desiccated
    Shipped InIce chest + Ice pads
    CAS380488-27-7(free)

    Certificates(CoA,COO,BSE/TSE and Analysis Chart)

    C of A & Other Certificates(BSE/TSE, COO):
    Analytical Chart:

    Find and download the COA for your product by matching the lot number on the packaging.

    8 results found

    Lot NumberCertificate TypeDateItem
    G2411404Certificate of AnalysisMar 21, 2024 N287721
    G2411405Certificate of AnalysisMar 21, 2024 N287721
    G2411406Certificate of AnalysisMar 21, 2024 N287721
    G2411407Certificate of AnalysisMar 21, 2024 N287721
    G2411433Certificate of AnalysisMar 21, 2024 N287721
    G2411434Certificate of AnalysisMar 21, 2024 N287721
    G2411435Certificate of AnalysisMar 21, 2024 N287721
    G2411436Certificate of AnalysisMar 21, 2024 N287721

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