19(R)-Hydroxy-prostaglandin E2 - 0.5 mg/ml in ethanol,>98%, high purity , CAS No.64625-54-3

Item Number

R336052

Grouped product items
SKU	Size	Availability	Price	Qty
R336052-50μg	50μg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$196.90
R336052-100μg	100μg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$369.90

a PGE2 metabolite that acts as a selective EP2 receptor agonist

View related series

Basic Description

Synonyms	7-[(1R,2R,3R)-2-[(3S,7R)-3,7-dihydroxyoct-1-enyl]-3-hydroxy-5-oxocyclopentyl]hept-5-enoic acid\|64625-54-3\|AC1MMZ8N\|CBiol_001999\|DTXSID50390584\|Bio1_000285\|Bio1_000774\|Bio1_001263
Specifications & Purity	0.5 mg/ml in ethanol,>98%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	19(R)-Hydroxy-prostaglandin E2 is a PGE2 metabolite that acts as a potent smooth muscle relaxant and a selective EP2 receptor agonist, contrary to PGE2, which can activate a variety of prostanoid receptor types. Reportedly, this compound occurs at significant levels in human seminal vesicles, but levels may vary across individuals possibly due to polymorphic expression of prostaglandin enzymatic mechanisms. It was found that microsomes of seminal vesicles metabolize exogenous prostaglandin E2 into 19(R)-Hydroxy-prostaglandin E2. This product was observed to activate plasma membrane A cyclase (adenylyl cyclase) and hepatocyte glycogen phosphorylase in isolated rockfish, but did not stimulate an FP-receptor preparation like PGE2.

Names and Identifiers

IUPAC Name	7-[(1R,2R,3R)-2-[(3S,7R)-3,7-dihydroxyoct-1-enyl]-3-hydroxy-5-oxocyclopentyl]hept-5-enoic acid
INCHI	InChI=1S/C20H32O6/c1-14(21)7-6-8-15(22)11-12-17-16(18(23)13-19(17)24)9-4-2-3-5-10-20(25)26/h2,4,11-12,14-17,19,21-22,24H,3,5-10,13H2,1H3,(H,25,26)/t14-,15+,16-,17-,19-/m1/s1
InChi Key	WTJYDBMHYPQFNJ-FSNPWBFUSA-N
Canonical SMILES	CC(CCCC(C=CC1C(CC(=O)C1CC=CCCCC(=O)O)O)O)O
Isomeric SMILES	C[C@H](CCC[C@@H](C=C[C@H]1[C@@H](CC(=O)[C@@H]1CC=CCCCC(=O)O)O)O)O
PubChem CID	3246806
Molecular Weight	368.46

Certificates

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

1 results found

Lot Number	Certificate Type	Date	Item
G2403742	Certificate of Analysis	Jun 13, 2024	R336052

Solubility

Soluble in DMSO (~100 mg/ml), DMF (~100 mg/ml), PBS (7.2) (~5 mg/ml), water (>5 mg/ml) at 25° C, ethanol, acetone, and ethyl acetate.

Refractive Index

n20D1.58

Boil Point(°C)

78° C

Solution Calculators

Determine the necessary mass, volume, or concentration for preparing a solution.

Determine the dilution needed to prepare a stock solution.

Basic Description