1a,1b-dihomo Prostaglandin E1 - 1 wt. % in methyl acetate, high purity , CAS No.A394344

Item Number

A394344

• Specifications & Purity: 1 wt. % in methyl acetate
• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads

Product Description

Prostaglandin E1 (PGE1) is not a major naturally occurring PG, but it is widely administered clinically for several indications including peripheral occlusive vascular disease, neonatal cardiology and erectile dysfunction. COX metabolism of the unusual fatty acid 10,13,16-docosatrienoic acid yields 1a,1b-dihomo PGE1. This rare metabolite has been recovered from incubations of whole sheep seminal vesicles, but has not been reported in humans. In ex vivo preparations of rat aorta and rat PRP, 1a,1b-dihomo PGE1 were found to be much less active than PGE1 itself.