1α,25-Dihydroxyvitamin D₃ (6,19,19-d₃) solution - 50μg/mL in ethanol, 97 atom% D, 96% (CP), high purity , CAS No.128723-16-0

Item Number

D466709

Grouped product items
SKU	Size	Availability	Price	Qty
D466709-1ml	1ml	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,245.90

Basic Description

Synonyms	Calcitriol-d3 \| 128723-16-0 \| (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]-1-deuterioethylidene]-4-(dideuteriomethylidene)cyclohexane-1,3-diol \| 1,25-Dihydroxyvitamin-D3-[2H3] \| AKO
Specifications & Purity	50μg/mL in ethanol, 97 atom% D, 96% (CP)
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	1α,25-Dihydroxyvitamin D3[1,25(OH)2D3], also known as calcitriol, plays a role in calcium and phosphate metabolism in humans. It also regulates insulin secretion and induces cellular differentiation.1α,25-Dihydroxyvitamin D3(6,19,19-d3) is a deuterated vitamin D3wherein C-6 and C-19 protons are replaced by deuterium.1α,25-Dihydroxyvitamin D3(6,19,19-d3) can be used as a stable isotope internal standard for accurate data interpretation in specific biological samples by mass spectrometry.

Names and Identifiers

IUPAC Name	(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]-1-deuterioethylidene]-4-(dideuteriomethylidene)cyclohexane-1,3-diol
INCHI	InChI=1S/C27H44O3/c1-18(8-6-14-26(3,4)30)23-12-13-24-20(9-7-15-27(23,24)5)10-11-21-16-22(28)17-25(29)19(21)2/h10-11,18,22-25,28-30H,2,6-9,12-17H2,1,3-5H3/b20-10+,21-11-/t18-,22-,23-,24+,25+,27-/m1/s1/i2D2,11D
InChi Key	GMRQFYUYWCNGIN-POLIPXRRSA-N
Canonical SMILES	CC(CCCC(C)(C)O)C1CCC2C1(CCCC2=CC=C3CC(CC(C3=C)O)O)C
Isomeric SMILES	[2H]C(=C\1[C@H](C[C@@H](C/C1=C(\[2H])/C=C/2\CCC[C@]3([C@H]2CC[C@@H]3[C@H](C)CCCC(C)(C)O)C)O)O)[2H]
PubChem CID	91820610
UN Number	1170
Molecular Weight	419.65

Flash Point(°F)

57.2 °F - closed cup

Flash Point(°C)

14.0 °C - closed cup

Safety and Hazards(GHS)

Pictogram(s)	GHS06, GHS08
Signal	Danger
Hazard Statements	H301:Toxic if swallowed H311:Toxic in contact with skin H330:Fatal if inhaled H372:Causes damage to organs through prolonged or repeated exposure H301+H311:Toxic if swallowed or in contact with skin
Precautionary Statements	P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P284:[In case of inadequate ventilation] Wear respiratory protection. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P330:Rinse mouth. P320:Specific treatment is urgent (see ... on this label). P361+P364:Take off immediately all contaminated clothing and wash it before reuse. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P316:Get emergency medical help immediately. P319:Get medical help if you feel unwell.
RIDADR	UN1170 - class 3 - PG 2 - Ethanol, solution

References

1. Jianqiong Zheng, Xiaohui Liu, Bingbing Zheng, Zhenzhen Zheng, Hongping Zhang, Jiayong Zheng, Congcong Sun, Haiying Chen, Jie Yang, Zuo Wang, Meimei Lin, Jingjing Chen, Qingdiao Zhou, Zhi Zheng, Xiaoming Xu, Hao Ying,. (2020-03-19) Maternal 25-Hydroxyvitamin D Deficiency Promoted Metabolic Syndrome and Downregulated Nrf2/CBR1 Pathway in Offspring.. Frontiers in pharmacology, ( 97-97 ). [PMID:32184720]

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Basic Description