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1H-indole-5-carboxamide(SD-169) - 97%, high purity , CAS No.1670-87-7

  • ≥97%
Item Number
H587593
Grouped product items
SKUSizeAvailabilityPrice Qty
H587593-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$39.90
H587593-250mg
250mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$52.90
H587593-1g
1g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$114.90

Basic Description

Synonyms1H-Indole-5-carboxamide|1670-87-7|Indole-5-carboxamide|SD-169|SD169|SD 169|5-Carboxamidoindole|1~{H}-indole-5-carboxamide|MLS006010711|SCHEMBL170646|CHEMBL1435541|BDBM93020|CHEBI:93599|1H-Indole-5-carboxamide, 97%|DTXSID50566323|GQMYQEAXTITUAE-UHFFFAOYSA-
Specifications & Purity≥97%
Storage TempProtected from light,Store at -20°C,Argon charged
Shipped InIce chest + Ice pads
Product Description

SD-169 is an orally active ATP-competitive inhibitor of p38α MAPK, with an IC50 of 3.2 nM. SD-169 also weakly inhibits p38β MAPK with an IC50 of 122 nM. SD-169 prevents the development and progression of diabetes by inhibiting T cell infiltration and activation.

Associated Targets

HDAC6 Tclin Histone deacetylase 6 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

KAT2B Tchem Histone acetyltransferase KAT2B 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ATAD5 Tbio ATPase family AAA domain-containing protein 5 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 1H-indole-5-carboxamide
INCHI InChI=1S/C9H8N2O/c10-9(12)7-1-2-8-6(5-7)3-4-11-8/h1-5,11H,(H2,10,12)
InChi Key GQMYQEAXTITUAE-UHFFFAOYSA-N
Canonical SMILES C1=CC2=C(C=CN2)C=C1C(=O)N
Isomeric SMILES C1=CC2=C(C=CN2)C=C1C(=O)N
WGK Germany 3
PubChem CID 14973220
Molecular Weight 160.17

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

Solubility DMSO: 10 mg/mL (62.43 mM)
Sensitivitylight sensitive

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H302:Harmful if swallowed

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P270:Do not eat, drink or smoke when using this product.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P330:Rinse mouth.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P301+P317:IF SWALLOWED: Get medical help.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 3

Related Documents

Solution Calculators