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Applications
Targets
G protein-coupled receptors (GPCRs)
Metabotropic glutamate receptors
(1R,5S,6S)-6-{[(3-chlorophenyl)methoxy]methyl}-3-({1-methyl-1H-imidazo[4,5-b]pyridin-2-yl}methyl)-3-azabicyclo[3.1.0]hexane , CAS No.R608829, Allosteric modulator of mGlu 2 receptor

(1R,5S,6S)-6-{[(3-chlorophenyl)methoxy]methyl}-3-({1-methyl-1H-imidazo[4,5-b]pyridin-2-yl}methyl)-3-azabicyclo[3.1.0]hexane , CAS No.R608829, Allosteric modulator of mGlu 2 receptor

Item Number

R608829

Grouped product items
SKU	Size	Availability	Price	Qty
R608829-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$570.90
R608829-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,000.90

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Basic Description

Synonyms	compound 19
Grade	Moligand™
Action Type	ALLOSTERIC MODULATOR
Mechanism of action	Allosteric modulator of mGlu 2 receptor

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

IUPAC Name	(1R,5S,6S)-6-{[(3-chlorophenyl)methoxy]methyl}-3-({1-methyl-1H-imidazo[4,5-b]pyridin-2-yl}methyl)-3-azabicyclo[3.1.0]hexane
INCHI	InChI=1S/C21H23ClN4O/c1-25-19-6-3-7-23-21(19)24-20(25)11-26-9-16-17(10-26)18(16)13-27-12-14-4-2-5-15(22)8-14/h2-8,16-18H,9-13H2,1H3/t16-,17+,18+
InChi Key	TYMQEQIUYIJHBZ-PIIMJCKOSA-N
Canonical SMILES	Clc1cccc(c1)COC[C@@H]1[C@@H]2[C@H]1CN(C2)Cc1nc2c(n1C)cccn2
Isomeric SMILES	CN1C2=C(N=CC=C2)N=C1CN3C[C@@H]4[C@H](C3)C4COCC5=CC(=CC=C5)Cl
PubChem CID	73755202

PubChem CID	73755202
GPCRdb Ligand	compound 19 [PMID: 18812259]

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