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Applications
Targets
G protein-coupled receptors (GPCRs)
Metabotropic glutamate receptors
2-{[(1R,5S,6S)-6-{[(5-chloropyridin-2-yl)methoxy]methyl}-3-azabicyclo[3.1.0]hexan-3-yl]methyl}-1-methyl-1H-1,3-benzodiazole , CAS No.R608714, Allosteric modulator of mGlu 2 receptor

2-{[(1R,5S,6S)-6-{[(5-chloropyridin-2-yl)methoxy]methyl}-3-azabicyclo[3.1.0]hexan-3-yl]methyl}-1-methyl-1H-1,3-benzodiazole , CAS No.R608714, Allosteric modulator of mGlu 2 receptor

Item Number

R608714

Grouped product items
SKU	Size	Availability	Price	Qty
R608714-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$570.90
R608714-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,000.90

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Basic Description

Synonyms	compound 14a
Grade	Moligand™
Action Type	ALLOSTERIC MODULATOR
Mechanism of action	Allosteric modulator of mGlu 2 receptor

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

IUPAC Name	2-{[(1R,5S,6S)-6-{[(5-chloropyridin-2-yl)methoxy]methyl}-3-azabicyclo[3.1.0]hexan-3-yl]methyl}-1-methyl-1H-1,3-benzodiazole
INCHI	InChI=1S/C21H23ClN4O/c1-25-20-5-3-2-4-19(20)24-21(25)11-26-9-16-17(10-26)18(16)13-27-12-15-7-6-14(22)8-23-15/h2-8,16-18H,9-13H2,1H3/t16-,17+,18+
InChi Key	XOVYESUODKGPJX-PIIMJCKOSA-N
Canonical SMILES	Clc1ccc(nc1)COC[C@@H]1[C@@H]2[C@H]1CN(C2)Cc1nc2c(n1C)cccc2
Isomeric SMILES	CN1C2=CC=CC=C2N=C1CN3C[C@@H]4[C@H](C3)C4COCC5=NC=C(C=C5)Cl
PubChem CID	73755200

PubChem CID	73755200
GPCRdb Ligand	compound 14a [PMID: 18812259]

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