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2-((2'-(5-Ethyl-3,4-diphenyl-1H-pyrazol-1-yl)-[1,1'-biphenyl]-3-yl)oxy)acetic acid - 10mM in DMSO, high purity , CAS No.300657-03-8
Potent and selective FABP4 inhibitor
Basic Description Synonyms 300657-03-8|BMS-309403|2-((2'-(5-Ethyl-3,4-diphenyl-1H-pyrazol-1-yl)-[1,1'-biphenyl]-3-yl)oxy)acetic acid|BMS 309403|BMS309403|FABP4 Inhibitor|[2'-(5-Ethyl-3,4-diphenyl-pyrazol-1-yl)-biphenyl-3-yloxy]acetic acid|((2'-(5-Ethyl-3,4-diphenyl-1H-pyrazol-1-yl) Specifications & Purity Moligand™, 10mM in DMSO Biochemical and Physiological Mechanisms Potent and selective fatty acid binding protein 4, adipocyte (FABP4) inhibitor (Kivalues are <2, 250 and 350 nM for FABP4, FABP3 and FABP5 respectively). Decreases fatty acid uptake in adipocytesin vitroand reduces atherosclerotic lesion area in a mouse m Storage Temp Store at -80°C Shipped In Ice chest + Ice pads Grade Moligand™
Names and Identifiers IUPAC Name 2-[3-[2-(5-ethyl-3,4-diphenylpyrazol-1-yl)phenyl]phenoxy]acetic acid INCHI InChI=1S/C31H26N2O3/c1-2-27-30(22-12-5-3-6-13-22)31(23-14-7-4-8-15-23)32-33(27)28-19-10-9-18-26(28)24-16-11-17-25(20-24)36-21-29(34)35/h3-20H,2,21H2,1H3,(H,34,35) InChi Key SJRVJRYZAQYCEE-UHFFFAOYSA-N Canonical SMILES CCC1=C(C(=NN1C2=CC=CC=C2C3=CC(=CC=C3)OCC(=O)O)C4=CC=CC=C4)C5=CC=CC=C5 Isomeric SMILES CCC1=C(C(=NN1C2=CC=CC=C2C3=CC(=CC=C3)OCC(=O)O)C4=CC=CC=C4)C5=CC=CC=C5 PubChem CID 16122583 Molecular Weight 474.55
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