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TKL:Tyrosine kinase-like
2-[4-(benzyloxy)phenyl]-2,5-dihydroxy-7-methoxy-3,4-dihydro-2H-1-benzopyran-4-one , CAS No.B607247, Inhibitor of receptor interacting serine/threonine kinase 1

2-[4-(benzyloxy)phenyl]-2,5-dihydroxy-7-methoxy-3,4-dihydro-2H-1-benzopyran-4-one , CAS No.B607247, Inhibitor of receptor interacting serine/threonine kinase 1

Item Number

B607247

Grouped product items
SKU	Size	Availability	Price	Qty
B607247-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,340.90
B607247-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,000.90

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Basic Description

Synonyms	6E+11
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of receptor interacting serine/threonine kinase 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

IUPAC Name	2-[4-(benzyloxy)phenyl]-2,5-dihydroxy-7-methoxy-3,4-dihydro-2H-1-benzopyran-4-one
INCHI	InChI=1S/C23H20O6/c1-27-18-11-19(24)22-20(25)13-23(26,29-21(22)12-18)16-7-9-17(10-8-16)28-14-15-5-3-2-4-6-15/h2-12,24,26H,13-14H2,1H3
InChi Key	OUAZLWHOOTXVCE-UHFFFAOYSA-N
Canonical SMILES	COc1cc2OC(O)(CC(=O)c2c(c1)O)c1ccc(cc1)OCc1ccccc1
Isomeric SMILES	COC1=CC(=C2C(=O)CC(OC2=C1)(C3=CC=C(C=C3)OCC4=CC=CC=C4)O)O
PubChem CID	132427685

PubChem CID	132427685

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1. Delehouzé C, Leverrier-Penna S, Le Cann F, Comte A, Jacquard-Fevai M, Delalande O, Desban N, Baratte B, Gallais I, Faurez F et al.. (2017) 6E11, a highly selective inhibitor of Receptor-Interacting Protein Kinase 1, protects cells against cold hypoxia-reoxygenation injury.. Sci Rep, 7 (1): (12931). [PMID:29018243]

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