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SKU

Size

Availability

Price

Qty

C129582-25g

25g

Available within 4-8 weeks(?)

$49.90

C129582-100g

100g

Available within 4-8 weeks(?)

$177.90

C129582-250g

250g

Available within 4-8 weeks(?)

$188.90

C129582-500g

500g

Available within 4-8 weeks(?)

$342.90

Basic Description

Synonyms	clofibric acid\|882-09-7\|2-(4-Chlorophenoxy)-2-methylpropanoic acid\|Chlorofibrinic acid\|2-(4-CHLOROPHENOXY)-2-METHYLPROPIONIC ACID\|Clofibrin\|Clofibrinic acid\|Chlorfibrinic acid\|PCIB\|Chlorophibrinic acid\|2-(4-Chlorophenoxy)isobutyric Acid\|2-(p-Chlorophenoxy
Specifications & Purity	≥98%
Shipped In	Normal
Product Description	Clofibric acid is a PPARα agonist and hypolipidemic agent. A hypolipidemic compound

Names and Identifiers

IUPAC Name	2-(4-chlorophenoxy)-2-methylpropanoic acid
INCHI	InChI=1S/C10H11ClO3/c1-10(2,9(12)13)14-8-5-3-7(11)4-6-8/h3-6H,1-2H3,(H,12,13)
InChi Key	TXCGAZHTZHNUAI-UHFFFAOYSA-N
Canonical SMILES	CC(C)(C(=O)O)OC1=CC=C(C=C1)Cl
Isomeric SMILES	CC(C)(C(=O)O)OC1=CC=C(C=C1)Cl
WGK Germany	3
RTECS	UE9455000
PubChem CID	2797
Molecular Weight	214.65
Reaxy-Rn	1874067

Certificates

Certificate of Analysis(COA)

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6 results found

Lot Number	Certificate Type	Date	Item
K2109348	Certificate of Analysis	Aug 15, 2023	C129582
K2109358	Certificate of Analysis	Aug 15, 2023	C129582
K2109360	Certificate of Analysis	Aug 15, 2023	C129582
K2109361	Certificate of Analysis	Aug 15, 2023	C129582
F2105033	Certificate of Analysis	Mar 14, 2023	C129582
B1525014	Certificate of Analysis	Sep 13, 2022	C129582

Chemical and Physical Properties

Solubility	Soluble in water (partly), 1eq. NaOH (100 mM), methanol (50 mg/ml), chloroform, and ethanol.
Melt Point(°C)	120-122°C

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H302:Harmful if swallowed
Precautionary Statements	P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help.
WGK Germany	3
RTECS	UE9455000
Reaxy-Rn	1874067
Merck Index	2378

References

1. K Sumida,H Kaneko,A Yoshitake. (1996-12-01) Inhibition of animal acetyl-coenzyme A carboxylase by 2-(p-chlorophenoxy)-2-methylpropionic acid and 2-ethylhexanoic acid.. Chemosphere, 33 ((11)): (2201-2207). [PMID:8938993]
2. J Clemy Monicka,C James. (2010-12-28) Vibrational spectra and natural bond orbital analysis of the herbicidal molecule 2(4-chlorophenoxy)-2-methyl propionic acid.. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 78 ((2)): (718-725). [PMID:21185226]
3. Eva Bacaicoa,Verónica Mora,Angel María Zamarreño,Marta Fuentes,Esther Casanova,José María García-Mina. (2011-03-18) Auxin: a major player in the shoot-to-root regulation of root Fe-stress physiological responses to Fe deficiency in cucumber plants.. Plant physiology and biochemistry : PPB, 49 ((5)): (545-556). [PMID:21411331]
4. Marco Zancani,Alberto Bertolini,Elisa Petrussa,Jana Krajňáková,Alessandro Piccolo,Riccardo Spaccini,Angelo Vianello. (2011-04-05) Fulvic acid affects proliferation and maturation phases in Abies cephalonica embryogenic cells.. Journal of plant physiology, 168 ((11)): (1226-1233). [PMID:21458883]
5. N R Neng,A S Mestre,A P Carvalho,J M F Nogueira. (2011-08-09) Cork-based activated carbons as supported adsorbent materials for trace level analysis of ibuprofen and clofibric acid in environmental and biological matrices.. Journal of chromatography. A, 1218 ((37)): (6263-6270). [PMID:21820664]
6. Manoharan Saravanan,Subramanian Karthika,Annamalai Malarvizhi,Mathan Ramesh. (2011-09-03) Ecotoxicological impacts of clofibric acid and diclofenac in common carp (Cyprinus carpio) fingerlings: hematological, biochemical, ionoregulatory and enzymological responses.. Journal of hazardous materials, 195 (188-194). [PMID:21885190]
7. K Okada,H Kanoh,K Mohri. (2011-10-27) Effects of clofibric acid on the biliary excretion of benoxaprofen glucuronide and taurine conjugate in rats.. Die Pharmazie, 66 ((10)): (777-783). [PMID:22026160]
8. Zubair Hasan,Jaewoo Jeon,Sung Hwa Jhung. (2012-01-27) Adsorptive removal of naproxen and clofibric acid from water using metal-organic frameworks.. Journal of hazardous materials, 209-210 (151-157). [PMID:22277335]
9. Jiabin Chen,Xuefei Zhou,Yalei Zhang,Yajie Qian,Haiping Gao. (2012-02-07) Interactions of acidic pharmaceuticals with human serum albumin: insights into the molecular toxicity of emerging pollutants.. Amino acids, 43 ((4)): (1419-1429). [PMID:22307229]
10. Julia Martín,M A Dolores Camacho-Muñoz,Juan Luis Santos,Irene Aparicio,Esteban Alonso. (2012-03-20) Distribution and temporal evolution of pharmaceutically active compounds alongside sewage sludge treatment. Risk assessment of sludge application onto soils.. Journal of environmental management, 102 (18-25). [PMID:22425875]
11. Byounghoon Hwang,Pengfei Wu,Robert A Harris. (2012-03-21) Additive effects of clofibric acid and pyruvate dehydrogenase kinase isoenzyme 4 (PDK4) deficiency on hepatic steatosis in mice fed a high saturated fat diet.. The FEBS journal, 279 ((10)): (1883-1893). [PMID:22429297]
12. Yaohuan Gao,Marc A Deshusses. (2012-03-24) Adsorption of clofibric acid and ketoprofen onto powdered activated carbon: effect of natural organic matter.. Environmental technology, 33 ((15-16)): (1719-1727). [PMID:22439557]
13. Dong Qing Zhang,Richard M Gersberg,Junfei Zhu,Tao Hua,K B S N Jinadasa,Soon Keat Tan. (2012-05-09) Batch versus continuous feeding strategies for pharmaceutical removal by subsurface flow constructed wetland.. Environmental pollution (Barking, Essex : 1987), 167 (124-131). [PMID:22564400]
14. Shuji Fukahori,Taku Fujiwara,Ryusei Ito,Naoyuki Funamizu. (2012-05-15) Photocatalytic decomposition of crotamiton over aqueous TiO(2) suspensions: determination of intermediates and the reaction pathway.. Chemosphere, 89 ((3)): (213-220). [PMID:22578794]
15. Christiane Hoppe-Jones,Eric R V Dickenson,Jörg E Drewes. (2012-09-04) The role of microbial adaptation and biodegradable dissolved organic carbon on the attenuation of trace organic chemicals during groundwater recharge.. The Science of the total environment, 437 (137-144). [PMID:22940041]
16. R Salgado,A Oehmen,G Carvalho,J P Noronha,M A M Reis. (2012-10-16) Biodegradation of clofibric acid and identification of its metabolites.. Journal of hazardous materials, 241-242 (182-189). [PMID:23062606]
17. Dong Qing Zhang,Richard M Gersberg,Tao Hua,Junfei Zhu,Wun Jern Ng,Soon Keat Tan. (2013-01-01) Assessment of plant-driven uptake and translocation of clofibric acid by Scirpus validus.. Environmental science and pollution research international, 20 ((7)): (4612-4620). [PMID:23274803]
18. Agustina Manassero,María Lucila Satuf,Orlando Mario Alfano. (2014-03-14) Kinetic modeling of the photocatalytic degradation of clofibric acid in a slurry reactor.. Environmental science and pollution research international, 22 ((2)): (926-937). [PMID:24622987]
19. Da-Bing Ren,Yan-Hua Qin,Yong-Huan Yun,Hong-Mei Lu,Xiao-Qing Chen,Yi-Zeng Liang. (2014-06-22) Using nonrandom two-liquid model for solvent system selection in counter-current chromatography.. Journal of chromatography. A, 1355 (80-85). [PMID:24951288]
20. Zein Shaban Ibrahim,Mohamed Mohamed Ahmed,Samir Ahmed El-Shazly,Mayumi Ishizuka,Shoichi Fujita. (2014-07-24) Clofibric acid induces hepatic CYP 2B1/2 via constitutive androstane receptor not via peroxisome proliferator activated receptor alpha in rat.. Bioscience, biotechnology, and biochemistry, 78 ((9)): (1550-1559). [PMID:25052003]
21. Mei-Quan Cai,Rong Wang,Li Feng,Li-Qiu Zhang. (2014-09-10) Determination of selected pharmaceuticals in tap water and drinking water treatment plant by high-performance liquid chromatography-triple quadrupole mass spectrometer in Beijing, China.. Environmental science and pollution research international, 22 ((3)): (1854-1867). [PMID:25196960]
22. Martin J A Schackmann,Rob Ofman,Inge M E Dijkstra,Ronald J A Wanders,Stephan Kemp. (2014-12-17) Enzymatic characterization of ELOVL1, a key enzyme in very long-chain fatty acid synthesis.. Biochimica et biophysica acta, 1851 ((2)): (231-237). [PMID:25499606]
23. Qiangqiang Sun,Yu Wang,Laisheng Li,Jishuai Bing,Yingxin Wang,Huihua Yan. (2015-01-16) Mechanism for enhanced degradation of clofibric acid in aqueous by catalytic ozonation over MnOx/SBA-15.. Journal of hazardous materials, 286 (276-284). [PMID:25590821]
24. Laurel K Dodgen,Aiko Ueda,Xiaoqin Wu,David R Parker,Jay Gan. (2015-01-17) Effect of transpiration on plant accumulation and translocation of PPCP/EDCs.. Environmental pollution (Barking, Essex : 1987), 198 (144-153). [PMID:25594843]
25. Carolina Nebot,Raquel Falcon,Kenneth G Boyd,Stuart W Gibb. (2015-03-05) Introduction of human pharmaceuticals from wastewater treatment plants into the aquatic environment: a rural perspective.. Environmental science and pollution research international, 22 ((14)): (10559-10568). [PMID:25735244]
26. Mireia Núñez,Francesc Borrull,Núria Fontanals,Eva Pocurull. (2015-03-18) Determination of pharmaceuticals in bivalves using QuEChERS extraction and liquid chromatography-tandem mass spectrometry.. Analytical and bioanalytical chemistry, 407 ((13)): (3841-3849). [PMID:25778794]
27. Carmen Lidia Chitescu,George Kaklamanos,Anca Ioana Nicolau,Alida Adriana Maria Linda Stolker. (2015-06-24) High sensitive multiresidue analysis of pharmaceuticals and antifungals in surface water using U-HPLC-Q-Exactive Orbitrap HRMS. Application to the Danube river basin on the Romanian territory.. The Science of the total environment, 532 (501-511). [PMID:26100729]
28. Tatsuki Fukami,Motoki Kariya,Takaya Kurokawa,Azumi Iida,Miki Nakajima. (2015-07-15) Comparison of substrate specificity among human arylacetamide deacetylase and carboxylesterases.. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 78 (47-53). [PMID:26164127]
29. Uwe Kunkel,Michael Radke. (2011-06-16) Reactive tracer test to evaluate the fate of pharmaceuticals in rivers.. Environmental science & technology, 45 ((15)): (6296-6302). [PMID:21671643]
30. Akihiko Hirose,Tohru Yamazaki,Takeshi Sakamoto,Katsuyoshi Sunaga,Tadashi Tsuda,Atsushi Mitsumoto,Naomi Kudo,Yoichi Kawashima. (2011-07-16) Clofibric acid increases the formation of oleic acid in endoplasmic reticulum of the liver of rats.. Journal of pharmacological sciences, 116 ((4)): (362-372). [PMID:21757842]
31. Denise Fernandes,Sabine Schnell,Cinta Porte. (2011-08-09) Can pharmaceuticals interfere with the synthesis of active androgens in male fish? An in vitro study.. Marine pollution bulletin, 62 ((10)): (2250-2253). [PMID:21820682]
32. Wenzhen Li,Shuguang Lu,Zhaofu Qiu,Kuangfei Lin. (2011-09-03) UV and VUV photolysis vs. UV/H2O2 and VUV/H2O2, treatment for removal of clofibric acid from aqueous solution.. Environmental technology, 32 ((9-10)): (1063-1071). [PMID:21882559]
33. Tohru Yamazaki,Hitomi Okada,Takeshi Sakamoto,Katsuyoshi Sunaga,Tadashi Tsuda,Atsushi Mitsumoto,Naomi Kudo,Yoichi Kawashima. (2012-01-10) Differential induction of stearoyl-CoA desaturase 1 and 2 genes by fibrates in the liver of rats.. Biological & pharmaceutical bulletin, 35 ((1)): (116-120). [PMID:22223347]
34. Dong Qing Zhang,Richard M Gersberg,Tao Hua,Junfei Zhu,Nguyen Anh Tuan,Soon Keat Tan. (2012-01-24) Pharmaceutical removal in tropical subsurface flow constructed wetlands at varying hydraulic loading rates.. Chemosphere, 87 ((3)): (273-277). [PMID:22264861]
35. Ladislav Tamás,Beáta Bočová,Jana Huttová,Ľubica Liptáková,Igor Mistrík,Katarína Valentovičová,Veronika Zelinová. (2012-07-17) Impact of the auxin signaling inhibitor p-chlorophenoxyisobutyric acid on short-term Cd-induced hydrogen peroxide production and growth response in barley root tip.. Journal of plant physiology, 169 ((14)): (1375-1381). [PMID:22795748]
36. Wilman A Cabrera-Lafaurie,Félix R Román,Arturo J Hernández-Maldonado. (2012-08-15) Transition metal modified and partially calcined inorganic-organic pillared clays for the adsorption of salicylic acid, clofibric acid, carbamazepine, and caffeine from water.. Journal of colloid and interface science, 386 ((1)): (381-391). [PMID:22889623]
37. Tohru Yamazaki,Michiko Wakabayashi,Erika Ikeda,Shizuyo Tanaka,Takeshi Sakamoto,Atsushi Mitsumoto,Naomi Kudo,Yoichi Kawashima. (2012-09-15) Induction of 1-acylglycerophosphocholine acyltransferase genes by fibrates in the liver of rats.. Biological & pharmaceutical bulletin, 35 ((9)): (1509-1515). [PMID:22975502]
38. Chao-meng Dai,Juan Zhang,Ya-lei Zhang,Xue-fei Zhou,Yan-ping Duan,Shu-guang Liu. (2013-02-26) Removal of carbamazepine and clofibric acid from water using double templates-molecularly imprinted polymers.. Environmental science and pollution research international, 20 ((8)): (5492-5501). [PMID:23436062]
39. Dong Qing Zhang,Richard M Gersberg,Tao Hua,Junfei Zhu,Manish Kumar Goyal,Wun Jern Ng,Soon Keat Tan. (2013-07-13) Fate of pharmaceutical compounds in hydroponic mesocosms planted with Scirpus validus.. Environmental pollution (Barking, Essex : 1987), 181 (98-106). [PMID:23845767]
40. Jheng-Jie Jiang,Chon-Lin Lee,Meng-Der Fang. (2014-01-21) Emerging organic contaminants in coastal waters: anthropogenic impact, environmental release and ecological risk.. Marine pollution bulletin, 85 ((2)): (391-399). [PMID:24439316]
41. Julia Martín,Juan Luis Santos,Irene Aparicio,Esteban Alonso. (2014-06-10) Pharmaceutically active compounds in sludge stabilization treatments: anaerobic and aerobic digestion, wastewater stabilization ponds and composting.. The Science of the total environment, 503-504 (97-104). [PMID:24909712]
42. Iwona Żur,Ewa Dubas,Monika Krzewska,Piotr Waligórski,Michał Dziurka,Franciszek Janowiak. (2014-09-28) Hormonal requirements for effective induction of microspore embryogenesis in triticale (× Triticosecale Wittm.) anther cultures.. Plant cell reports, 34 ((1)): (47-62). [PMID:25261160]
43. Laurence Berthod,Gary Roberts,David C Whitley,Alan Sharpe,Graham A Mills. (2014-10-10) A solid-phase extraction method for rapidly determining the adsorption coefficient of pharmaceuticals in sewage sludge.. Water research, 67 (292-298). [PMID:25299795]
44. Hsiang-Wen Chen,Ko-Hsuan Shao,Shu-Jen Wang. (2015-01-27) Light-modulated seminal wavy roots in rice mediated by nitric oxide-dependent signaling.. Protoplasma, 252 ((5)): (1291-1304). [PMID:25619895]
45. Mercedes Becerra-Herrera,Luis Honda,Pablo Richter. (2015-11-13) Ultra-high-performance liquid chromatography-Time-of-flight high resolution mass spectrometry to quantify acidic drugs in wastewater.. Journal of chromatography. A, 1423 (96-103). [PMID:26559617]

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2-(4-Chlorophenoxy)isobutyric Acid - ≥98%, high purity , CAS No.882-09-7

Basic Description

Names and Identifiers

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

Safety and Hazards(GHS)

Related Documents

References

Solution Calculators

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

SKU	Size	Availability	Price
C129582-25g	25g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$49.90
C129582-100g	100g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$177.90
C129582-250g	250g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$188.90
C129582-500g	500g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$342.90