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2,4'-Dibromoacetophenone - for HPLC derivatization, ≥99.0% (HPLC), high purity , CAS No.99-73-0
Cell-permeable, non-ATP competitive GSK-3β inhibitor. Phospholipase A 2 inhibitor.
Basic Description Synonyms 2,4'-Dibromoacetophenone|99-73-0|2-Bromo-1-(4-bromophenyl)ethanone|p-Bromophenacyl bromide|4-Bromophenacyl bromide|Ethanone, 2-bromo-1-(4-bromophenyl)-|2-bromo-1-(4-bromophenyl)-ethanone|2-bromo-1-(4-bromophenyl)ethan-1-one|4'-Bromophenacyl bromide|132309 Specifications & Purity for HPLC derivatization, ≥99%(HPLC) Biochemical and Physiological Mechanisms Cell-permeable, non-ATP competitive GSK-3β inhibitor (IC 50 = 0.5 µM). Phospholipase A 2 inhibitor. Inhibits prostaglandin D2 synthesis from arachidonic acid. Shipped In Normal Grade for HPLC derivatization Note Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Names and Identifiers IUPAC Name 2-bromo-1-(4-bromophenyl)ethanone INCHI InChI=1S/C8H6Br2O/c9-5-8(11)6-1-3-7(10)4-2-6/h1-4H,5H2 InChi Key FKJSFKCZZIXQIP-UHFFFAOYSA-N Canonical SMILES C1=CC(=CC=C1C(=O)CBr)Br Isomeric SMILES C1=CC(=CC=C1C(=O)CBr)Br WGK Germany 2 RTECS AM6950000 PubChem CID 7454 UN Number 3261 Packing Group II Molecular Weight 277.94 Beilstein 607604 Reaxy-Rn 607604
Chemical and Physical Properties Safety and Hazards(GHS) Pictogram(s) GHS05 Signal Danger Hazard Statements H314: Causes severe skin burns and eye damage
H303: May be harmful if swallowed
Precautionary Statements P280: Wear protective gloves/protective clothing/eye protection/face protection.
P321: Specific treatment (see ... on this label).
P405: Store locked up.
P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P260: Do not breathe dust/fume/gas/mist/vapors/spray.
P301+P330+P331: IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P304+P340: IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P363: Wash contaminated clothing before reuse.
P305+P354+P338: IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing.
P302+P361+P354: IF ON SKIN: Take off Immediately all contaminated clothing. Immediately rinse with water for several minutes.
P316: Get emergency medical help immediately.
WGK Germany 2 RTECS AM6950000 Reaxy-Rn 607604 Merck Index 1427
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