Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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D100520-1g | 1g | In stock | $11.90 | |
D100520-5g | 5g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $35.90 | |
D100520-25g | 25g | In stock | $125.90 | |
D100520-100g | 100g | In stock | $352.90 |
Synonyms | 51166-71-3|2,6-Di-O-methyl-beta-cyclodextrin|2,6-Di-O-methyl-|A-cyclodextrin|Heptakis(2,6-di-O-methyl)-beta-cyclodextrin|Di-O-methyl-beta-cyclodextrin|5FJP73E35O|Dimethyl-beta-cyclodextrin|MFCD00011616|UNII-5FJP73E35O|2,6-Dimethyl-beta-cyclodextrin|heptak |
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Specifications & Purity | ≥98% |
Storage Temp | Room temperature |
Shipped In | Normal |
Product Description | Solubility in water: 800 g / L (25 ° C), dissolved in methanol, ethanol, acetone, pyridine, DMSO, and THF. Heptakis(2,6-di-O-methyl)-β-cyclodextrin is a hydrophilic derivative of cyclodextrin that possesses the ability to effectively dissolve lipophilic drugs like steroid hormones, vitamins A, E, and K, etc. It can be utilized to increase the dissolution and bioavailability of weakly water-soluble pharmaceutical compounds. Complexes are more soluble in aqueous solution than the corresponding complexes of β-cyclodextrin; Stimulation of fatty acid synthesis Reactant involved in: • Physicochemical studies of inclusion complexes • Probing diffusion and single molecule interactions with reconstituted membrane proteins • Interactions with micelles causing micellar rupture • Studying cellular transport, used as a cell penetration enhancer • Physicochemical and biopharmaceutical improvement of drugs particularly with solubilization and stability • Interactions with cholesterol Heptakis(2,6-di-O-methyl)-β-cyclodextrin may be used: • To measure the equilibrium constant of its complexes with various enantiomeric pairs of chiral nitroxides by electron paramagnetic resonance (EPR) spectroscopy. • To study the crystal structure of its complex with n-butyl acrylate and isobornyl acrylate using X-ray diffraction (XRD). • As a chiral selector to resolve amphetamine related drugs by capillary zone electrophoresis. |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Pubchem Sid | 488196563 |
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Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488196563 |
IUPAC Name | (1S,3R,5R,6S,8R,10R,11S,13R,15R,16S,18R,20R,21S,23R,25R,26S,28R,30R,31S,33R,35R,36S,37R,38S,39R,40S,41R,42S,43R,44S,45R,46S,47R,48S,49R)-37,39,41,43,45,47,49-heptamethoxy-5,10,15,20,25,30,35-heptakis(methoxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29,32,34-tetradecaoxaoctacyclo[31.2.2.23,6.28,11.213,16.218,21.223,26.228,31]nonatetracontane-36,38,40,42,44,46,48-heptol |
INCHI | InChI=1S/C56H98O35/c1-64-15-22-36-29(57)43(71-8)50(78-22)86-37-23(16-65-2)80-52(45(73-10)30(37)58)88-39-25(18-67-4)82-54(47(75-12)32(39)60)90-41-27(20-69-6)84-56(49(77-14)34(41)62)91-42-28(21-70-7)83-55(48(76-13)35(42)63)89-40-26(19-68-5)81-53(46(74-11)33(40)61)87-38-24(17-66-3)79-51(85-36)44(72-9)31(38)59/h22-63H,15-21H2,1-14H3/t22-,23-,24-,25-,26-,27-,28-,29+,30+,31+,32+,33+,34+,35+,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48-,49-,50-,51-,52-,53-,54-,55-,56-/m1/s1 |
InChi Key | QGKBSGBYSPTPKJ-UZMKXNTCSA-N |
Canonical SMILES | COCC1C2C(C(C(O1)OC3C(OC(C(C3O)OC)OC4C(OC(C(C4O)OC)OC5C(OC(C(C5O)OC)OC6C(OC(C(C6O)OC)OC7C(OC(C(C7O)OC)OC8C(OC(O2)C(C8O)OC)COC)COC)COC)COC)COC)COC)OC)O |
Isomeric SMILES | COC[C@@H]1[C@@H]2[C@@H]([C@H]([C@H](O1)O[C@@H]3[C@H](O[C@@H]([C@@H]([C@H]3O)OC)O[C@@H]4[C@H](O[C@@H]([C@@H]([C@H]4O)OC)O[C@@H]5[C@H](O[C@@H]([C@@H]([C@H]5O)OC)O[C@@H]6[C@H](O[C@@H]([C@@H]([C@H]6O)OC)O[C@@H]7[C@H](O[C@@H]([C@@H]([C@H]7O)OC)O[C@@H]8[C@H](O[C@H](O2)[C@@H]([C@H]8O)OC)COC)COC)COC)COC)COC)COC)OC)O |
WGK Germany | 3 |
PubChem CID | 10171019 |
Molecular Weight | 1331.36 |
Beilstein | 1679140 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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H2409332 | Certificate of Analysis | Jul 22, 2024 | D100520 |
H2409333 | Certificate of Analysis | Jul 22, 2024 | D100520 |
H2409334 | Certificate of Analysis | Jul 22, 2024 | D100520 |
F2420135 | Certificate of Analysis | Apr 29, 2024 | D100520 |
F2420136 | Certificate of Analysis | Apr 29, 2024 | D100520 |
F2420137 | Certificate of Analysis | Apr 29, 2024 | D100520 |
D2408098 | Certificate of Analysis | Aug 28, 2023 | D100520 |
J2326037 | Certificate of Analysis | Aug 28, 2023 | D100520 |
J2326038 | Certificate of Analysis | Aug 28, 2023 | D100520 |
F2314226 | Certificate of Analysis | Jun 29, 2022 | D100520 |
F2314235 | Certificate of Analysis | Jun 29, 2022 | D100520 |
H2315304 | Certificate of Analysis | Jun 29, 2022 | D100520 |
J2214557 | Certificate of Analysis | Jun 29, 2022 | D100520 |
J2214558 | Certificate of Analysis | Jun 29, 2022 | D100520 |
J2214559 | Certificate of Analysis | Jun 29, 2022 | D100520 |
J2214804 | Certificate of Analysis | Jun 29, 2022 | D100520 |
Sensitivity | moisture sensitive |
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Flash Point(°C) | 187°C |
Melt Point(°C) | 180-182°C |
WGK Germany | 3 |
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