Aminoethyl methacrylate hydrochloride (AMA) is an amine based methacrylic monomer used in the production of polymers and copolymers that are utilized in a wide range of applications, including coatings, adhesives, and medical devices. It is a highly reactive monomer due to the presence of the methacrylate group, which enables it to undergo both free radical polymerization and other polymerization reactions. Due to its biocompatibility and low toxicity, it is widely used in biomedical research and as a crosslinking agent for hydrogels and other biomaterials. It is used in the synthesis of poly (2-aminoethylmethacrylate), a biocompatible cationic polymer widely used in the biomedical field.
Application:
2-Aminoethylmethacrylate hydrochloride(AMA) can be used as a precursor to synthesize: Homo and copolymer brushes of AMA, which can be used to tune the electrochemical properties of silicon wafers. Poly(3-hydroxybutyrate) based polyurethane/urea composite scaffolds for tissue engineering applications. Antimicrobial bacterial cellulose/poly (AMA) nanocomposites. Polymer incorporation imparts mechanical properties and antimicrobial activity to bacterial cellulose membranes. It can also be used for the efficient functionalization of hyaluronic acid via triazine-mediated amidation.
1.Haifeng Ni, Sunxiang Qian, Jie Lu, Jie Feng, Xiao-zhou Mou, Jing Zhang. (2023) Natural Polysaccharide Delivery Platforms with Multiscale Structure Used for Cancer Chemoimmunotherapy. MOLECULAR PHARMACEUTICS, (28):[PMID:37752866]
2.Hao Ye, Tian-Hao Li, Yu-Qi Huang, Jia-Min Jin, Jin-Yan Fei, Ming-Bang Wu, Juming Yao. (2023) Amyloid-like coatings decorated electrodes boost the uranium electro-adsorption from seawater. CHEMICAL ENGINEERING JOURNAL, 451 (138615). [PMID:]
3.Lingling Pan, Dawei Jiang, Luqi Pan, Zhizhen Meng, Yangyang Zhuang, Yueyue Huang, Fanrong Ye, Changcan Shi, Jie Chen, Jingye Pan. (2022) ICAM-1-targeted and antibacterial peptide modified polymeric nanoparticles for specific combating sepsis. MATERIALS & DESIGN, 222 (111007). [PMID:]
4.Jiajun Qin, Ming Li, Ming Yuan, Xinglei Shi, Jiliang Song, Yiyan He, Hongli Mao, Deling Kong, Zhongwei Gu. (2022) Gallium(III)-Mediated Dual-Cross-Linked Alginate Hydrogels with Antibacterial Properties for Promoting Infected Wound Healing. ACS Applied Materials & Interfaces, 14 (19):(22426–22442). [PMID:35533377]
5.Ye Han Yan,Muhammad Atif,Ren Yong Liu,Hai Kun Zhu,Li Juan Chen. (2019-12-04) Design of comb-like poly(2-methyl-2-oxazoline) and its rapid co-deposition with dopamine for the study of antifouling properties.. Journal of biomaterials science. Polymer edition, 31 ((4)):(423-438). [PMID:31791188]
References
1.Haifeng Ni, Sunxiang Qian, Jie Lu, Jie Feng, Xiao-zhou Mou, Jing Zhang. (2023) Natural Polysaccharide Delivery Platforms with Multiscale Structure Used for Cancer Chemoimmunotherapy. MOLECULAR PHARMACEUTICS, (28):[PMID:37752866]
2.Hao Ye, Tian-Hao Li, Yu-Qi Huang, Jia-Min Jin, Jin-Yan Fei, Ming-Bang Wu, Juming Yao. (2023) Amyloid-like coatings decorated electrodes boost the uranium electro-adsorption from seawater. CHEMICAL ENGINEERING JOURNAL, 451 (138615). [PMID:]
3.Lingling Pan, Dawei Jiang, Luqi Pan, Zhizhen Meng, Yangyang Zhuang, Yueyue Huang, Fanrong Ye, Changcan Shi, Jie Chen, Jingye Pan. (2022) ICAM-1-targeted and antibacterial peptide modified polymeric nanoparticles for specific combating sepsis. MATERIALS & DESIGN, 222 (111007). [PMID:]
4.Jiajun Qin, Ming Li, Ming Yuan, Xinglei Shi, Jiliang Song, Yiyan He, Hongli Mao, Deling Kong, Zhongwei Gu. (2022) Gallium(III)-Mediated Dual-Cross-Linked Alginate Hydrogels with Antibacterial Properties for Promoting Infected Wound Healing. ACS Applied Materials & Interfaces, 14 (19):(22426–22442). [PMID:35533377]
5.Ye Han Yan,Muhammad Atif,Ren Yong Liu,Hai Kun Zhu,Li Juan Chen. (2019-12-04) Design of comb-like poly(2-methyl-2-oxazoline) and its rapid co-deposition with dopamine for the study of antifouling properties.. Journal of biomaterials science. Polymer edition, 31 ((4)):(423-438). [PMID:31791188]
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