Discover 2-Arachidonoyl-1-palmitoyl-sn-glycero-3-phosphocholine by Aladdin Scientific in ≥ 95%, 50 mg/mL chloroform solution for only $329.90. Available - in Ligands at Aladdin Scientific. a phospholipid that contains palmitic acid and arachidonic acid at the sn-1 and sn-2 positions. Tags: 15952,15953,15954.
Basic Description
Synonyms
PAPC | 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine | 16:0-20:4 PC | PC(16:0/20:4(5Z,8Z,11Z,14Z)) | PC(16:0/20:4)
Specifications & Purity
≥ 95%, 50 mg/mL chloroform solution
Storage Temp
Store at -80°C
Shipped In
Ice chest + Ice pads
Product Description
2-Arachidonoyl-1-palmitoyl-sn-glycero-3-phosphocholine is a phospholipid that contains palmitic acid and arachidonic acid at the sn-1 and sn-2 positions. 2-Arachidonoyl-1-palmitoyl-sn-glycero-3-phosphocholine can be found naturally in biological membranes. In vivo, 2-Arachidonoyl-1-palmitoyl-sn-glycero-3-phosphocholine is oxidized, and its products are involved in chronic inflammation and vascular disease. 2-Arachidonoyl-1-palmitoyl-sn-glycero-3-phosphocholine has been utilized in the studies of oxidized phospholipid signaling. Isolated human myeloma cells showed decreased levels of 2-Arachidonoyl-1-palmitoyl-sn-glycero-3-phosphocholine.
product description：
Phosphatidylcholine (PC) is one of the major glycerophospholipids of the eukaryotic membranes. PC is zwitterionic. PC is synthesized via two pathways in higher eukaryotes like the triple methylation of phosphatidylethanolamine and the cytidine diphosphate (CDP)-choline pathway.
application：
16:0-20:4 PC is suitable for use:
in the preparation of auto-oxidised phospholipid for electrospray ionisation mass spectroscopic (ESI-MS) analysis
in liposome preparation for the treatment of organoid
as antigen in enzyme linked immunosorbent assay (ELISA) for the detection of autoantibodies to phospholipids
Biochemical/Physiological Effects：
Phosphatidylcholine (PC) is essential for maintaining the structure and functions of the membrane. PC is the substrate for sphingomyelin synthesis. PC is the precursor for various second messenger like phosphatidic acid, lysophosphatidic acid, diacylglycerol. PC is the dominant phospholipid present in cancer and neo-neoplastic tissues. Level of 16:0-20:4 PC is less in multiple myeloma cells than in normal plasma cells.
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