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E113696-25ml

25ml

In stock

$17.90

E113696-100ml

100ml

In stock

$30.90

E113696-500ml

500ml

Available within 4-8 weeks(?)

$54.90

Basic Description

Synonyms	2-ETHYLHEXYL SALICYLATE\|Octisalate\|118-60-5\|2-Ethylhexyl 2-hydroxybenzoate\|Ethylhexyl salicylate\|Ethyl hexyl salicylate\|Sunarome O\|Sunarome WMO\|Benzoic acid, 2-hydroxy-, 2-ethylhexyl ester\|Uvinul\|Escalol\|USAF DO-11\|Neo Heliopan\|Salicylic acid, 2-ethylhexy
Specifications & Purity	≥98%
Shipped In	Normal
Note	10L卖完停产，不再备货

Associated Targets

TRPA1 Tclin Transient receptor potential cation channel subfamily A member 1 0 Activities

Discover Target: TRPA1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PMP22 Tbio Peripheral myelin protein 22 0 Activities

Discover Target: PMP22

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

LMNA Tbio Prelamin-A/C 0 Activities

Discover Target: LMNA

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NFE2L2 Tchem Nuclear factor erythroid 2-related factor 2 0 Activities

Discover Target: NFE2L2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

Pubchem Sid	488180765
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488180765
IUPAC Name	2-ethylhexyl 2-hydroxybenzoate
INCHI	InChI=1S/C15H22O3/c1-3-5-8-12(4-2)11-18-15(17)13-9-6-7-10-14(13)16/h6-7,9-10,12,16H,3-5,8,11H2,1-2H3
InChi Key	FMRHJJZUHUTGKE-UHFFFAOYSA-N
Canonical SMILES	CCCCC(CC)COC(=O)C1=CC=CC=C1O
Isomeric SMILES	CCCCC(CC)COC(=O)C1=CC=CC=C1O
RTECS	VO3150000
PubChem CID	8364
Molecular Weight	250.33
Beilstein	2730664
Reaxy-Rn	2730664

Certificates

Certificate of Analysis(COA)

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5 results found

Lot Number	Certificate Type	Date	Item
G1919186	Certificate of Analysis	May 08, 2023	E113696
B2315199	Certificate of Analysis	Mar 01, 2023	E113696
B2315197	Certificate of Analysis	Feb 28, 2023	E113696
C2225046	Certificate of Analysis	Apr 13, 2022	E113696
D1824085	Certificate of Analysis	Feb 16, 2022	E113696

Chemical and Physical Properties

Solubility	Insoluble in water; Soluble in Alcohol
Sensitivity	Light Sensitive
Refractive Index	1.502
Flash Point(°F)	＞110℃
Flash Point(°C)	＞110℃
Boil Point(°C)	189-190°C

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation
Precautionary Statements	P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P264:Wash hands [and …] thoroughly after handling. P362+P364:Take off contaminated clothing and wash it before reuse. P332+P317:If skin irritation occurs: Get medical help.
RTECS	VO3150000
Reaxy-Rn	2730664
Merck Index	6770

References

1. R Jiang,C G Hayden,R J Prankerd,M S Roberts,H A Benson. (1996-06-28) High-performance liquid chromatographic assay for common sunscreening agents in cosmetic products, bovine serum albumin solution and human plasma.. Journal of chromatography. B, Biomedical applications, 682 ((1)): (137-145). [PMID:8832434]
2. R Jiang,M S Roberts,R J Prankerd,H A Benson. (1997-07-01) Percutaneous absorption of sunscreen agents from liquid paraffin: self-association of octyl salicylate and effects on skin flux.. Journal of pharmaceutical sciences, 86 ((7)): (791-796). [PMID:9232518]
3. M McVean,D C Liebler. (1997-08-01) Inhibition of UVB induced DNA photodamage in mouse epidermis by topically applied alpha-tocopherol.. Carcinogenesis, 18 ((8)): (1617-1622). [PMID:9276638]
4. T M Morgan,B L Reed,B C Finnin. (1998-10-06) Enhanced skin permeation of sex hormones with novel topical spray vehicles.. Journal of pharmaceutical sciences, 87 ((10)): (1213-1218). [PMID:9758679]
5. M McVean,D C Liebler. (1999-04-16) Prevention of DNA photodamage by vitamin E compounds and sunscreens: roles of ultraviolet absorbance and cellular uptake.. Molecular carcinogenesis, 24 ((3)): (169-176). [PMID:10204801]
6. P Clarys,B Gabard,R Lambrecht,A Barel,E Bieli,S Lüdi. (2001-09-05) There is no influence of a temperature rise on in vivo adsorption of UV filters into the stratum corneum.. Journal of dermatological science, 27 ((2)): (77-81). [PMID:11532370]
7. Rajagopal Krishnan,Aaron Carr,Elizabeth Blair,Thomas M Nordlund. (2004-08-05) Optical spectroscopy of hydrophobic sunscreen molecules adsorbed to dielectric nanospheres.. Photochemistry and photobiology, 79 ((6)): (531-539). [PMID:15291305]
8. L R Gaspar,P M B G Maia Campos. (2005-11-18) Evaluation of the photostability of different UV filter combinations in a sunscreen.. International journal of pharmaceutics, 307 ((2)): (123-128). [PMID:16289662]
9. M Singh,M H Beck. (2006-12-21) Octyl salicylate: a new contact sensitivity.. Contact dermatitis, 56 ((1)): (48-48). [PMID:17177714]
10. Rajagopal Krishnan,Thomas M Nordlund. (2007-10-27) Fluorescence dynamics of three UV-B sunscreens.. Journal of fluorescence, 18 ((1)): (203-217). [PMID:17963026]
11. A Lapczynski,D McGinty,L Jones,C S Letizia,A M Api. (2007-11-23) Fragrance material review on trans-2-hexenyl salicylate.. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 45 Suppl 1 (S406-S409). [PMID:18031887]
12. A Lapczynski,D McGinty,L Jones,C S Letizia,A M Api. (2007-11-23) Fragrance material review on ethyl hexyl salicylate.. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 45 Suppl 1 (S393-S396). [PMID:18031898]
13. N Negreira,I Rodríguez,M Ramil,E Rubí,R Cela. (2009-03-21) Sensitive determination of salicylate and benzophenone type UV filters in water samples using solid-phase microextraction, derivatization and gas chromatography tandem mass spectrometry.. Analytica chimica acta, 638 ((1)): (36-44). [PMID:19298877]
14. N Negreira,I Rodríguez,E Rubí,R Cela. (2009-06-23) Determination of selected UV filters in indoor dust by matrix solid-phase dispersion and gas chromatography-tandem mass spectrometry.. Journal of chromatography. A, 1216 ((31)): (5895-5902). [PMID:19539293]
15. Charlotte Gotthard Mortz,Henrik Thormann,An Goossens,Klaus Ejner Andersen. (2010-03-18) Allergic contact dermatitis from ethylhexyl salicylate and other salicylates.. Dermatitis : contact, atopic, occupational, drug, 21 ((2)): (E7-10). [PMID:20233542]
16. Hongtao Liu,Ling Liu,Yiquan Xiong,Xuemei Yang,Tiangang Luan. (2010-06-29) Simultaneous determination of UV filters and polycyclic musks in aqueous samples by solid-phase microextraction and gas chromatography-mass spectrometry.. Journal of chromatography. A, 1217 ((43)): (6747-6753). [PMID:20580369]
17. Fernanda Maria Pinto Vilela,Yris Maria Fonseca,José Roberto Jabor,Fabiana T M C Vicentini,Maria José Vieira Fonseca. (2011-11-01) Effect of ultraviolet filters on skin superoxide dismutase activity in hairless mice after a single dose of ultraviolet radiation.. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 80 ((2)): (387-392). [PMID:22036989]
18. Beatriz Albero,Consuelo Sánchez-Brunete,Esther Miguel,Rosa A Pérez,José L Tadeo. (2012-06-12) Determination of selected organic contaminants in soil by pressurized liquid extraction and gas chromatography tandem mass spectrometry with in situ derivatization.. Journal of chromatography. A, 1248 (9-17). [PMID:22683186]
19. P Santos,A C Watkinson,J Hadgraft,M E Lane. (2012-09-25) Influence of penetration enhancer on drug permeation from volatile formulations.. International journal of pharmaceutics, 439 ((1-2)): (260-268). [PMID:23000063]
20. Ana Flo Sierra,Maria L Garduño Ramírez,Ana C Calpena Campmany,Adolfina Ruiz Martínez,Beatriz Clares Naveros. (2012-11-20) In vivo and in vitro evaluation of the use of a newly developed melatonin loaded emulsion combined with UV filters as a protective agent against skin irradiation.. Journal of dermatological science, 69 ((3)): (202-214). [PMID:23159282]
21. Rita Celano,Anna Lisa Piccinelli,Luca Campone,Luca Rastrelli. (2014-06-19) Ultra-preconcentration and determination of selected pharmaceutical and personal care products in different water matrices by solid-phase extraction combined with dispersive liquid-liquid microextraction prior to ultra high pressure liquid chromatography tandem mass spectrometry analysis.. Journal of chromatography. A, 1355 (26-35). [PMID:24939087]
22. Yi Li,Min Zhang,Yaoxia Yang,Xuemei Wang,Xinzhen Du. (2014-07-20) Electrochemical in situ fabrication of titanium dioxide-nanosheets on a titanium wire as a novel coating for selective solid-phase microextraction.. Journal of chromatography. A, 1358 (60-67). [PMID:25037779]
23. Marina G Pintado-Herrera,Eduardo González-Mazo,Pablo A Lara-Martín. (2014-12-03) Atmospheric pressure gas chromatography-time-of-flight-mass spectrometry (APGC-ToF-MS) for the determination of regulated and emerging contaminants in aqueous samples after stir bar sorptive extraction (SBSE).. Analytica chimica acta, 851 (1-13). [PMID:25440658]
24. Wenlan Song,Mei Guo,Yida Zhang,Min Zhang,Xuemei Wang,Xinzhen Du. (2015-02-11) Fabrication and application of zinc-zinc oxide nanosheets coating on an etched stainless steel wire as a selective solid-phase microextraction fiber.. Journal of chromatography. A, 1384 (28-36). [PMID:25662065]
25. S C Cunha,J O Fernandes,L Vallecillos,G Cano-Sancho,J L Domingo,E Pocurull,F Borrull,A L Maulvault,F Ferrari,M Fernandez-Tejedor,F Van den Heuvel,M Kotterman. (2015-05-20) Co-occurrence of musk fragrances and UV-filters in seafood and macroalgae collected in European hotspots.. Environmental research, 143 ((Pt B)): (65-71). [PMID:25985745]
26. Yida Zhang,Yaoxia Yang,Yi Li,Min Zhang,Xuemei Wang,Xinzhen Du. (2015-05-23) Growth of cedar-like Au nanoparticles coating on an etched stainless steel wire and its application for selective solid-phase microextraction.. Analytica chimica acta, 876 (55-62). [PMID:25998458]
27. Nicola Parisi,Paul J Matts,Rebecca Lever,Jonathan Hadgraft,Majella E Lane. (2015-08-04) Preparation and characterisation of hexamidine salts.. International journal of pharmaceutics, 493 ((1-2)): (404-411). [PMID:26235920]
28. Juan L Benedé,Alberto Chisvert,Dimosthenis L Giokas,Amparo Salvador. (2015-11-26) Determination of ultraviolet filters in bathing waters by stir bar sorptive-dispersive microextraction coupled to thermal desorption-gas chromatography-mass spectrometry.. Talanta, 147 (246-252). [PMID:26592603]
29. K A Walters,K R Brain,D Howes,V J James,A L Kraus,N M Teetsel,M Toulon,A C Watkinson,S D Gettings. (1998-02-04) Percutaneous penetration of octyl salicylate from representative sunscreen formulations through human skin in vitro.. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 35 ((12)): (1219-1225). [PMID:9449227]
30. Daniel W Shaw. (2006-09-08) Allergic contact dermatitis from octisalate and cis-3-hexenyl salicylate.. Dermatitis : contact, atopic, occupational, drug, 17 ((3)): (152-155). [PMID:16956469]
31. Rajagopal Krishnan,Craig A Elmets,Thomas M Nordlund. (2006-10-05) A new method to test the effectiveness of sunscreen ingredients in a novel nano-surface skin cell mimic.. Photochemistry and photobiology, 82 ((6)): (1549-1556). [PMID:17017843]

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2-Ethylhexyl salicylate - 98%, high purity , CAS No.118-60-5