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2-Methylbutyryl-L-carnitine - ≥97.0% (HPLC), high purity , CAS No.256928-75-3

  • ≥97%(HPLC)
Item Number
M464442
Grouped product items
SKUSizeAvailabilityPrice Qty
M464442-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$89.90
M464442-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$349.90
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Non natural amino acid derivatives

Basic Description

Synonyms2-Methylbutyroylcarnitine|31023-25-3|3-((2-Methylbutanoyl)oxy)-4-(trimethylammonio)butanoate|2-Methylbutyrylcarnitine|256928-75-3|3-(2-methylbutanoyloxy)-4-(trimethylazaniumyl)butanoate|3-[(2-methylbutanoyl)oxy]-4-(trimethylazaniumyl)butanoate|3-(2-METHYL
Specifications & Purity≥97.0% (HPLC)
Storage TempStore at 2-8°C
Shipped InWet ice

Names and Identifiers

IUPAC Name 3-(2-methylbutanoyloxy)-4-(trimethylazaniumyl)butanoate
INCHI InChI=1S/C12H23NO4/c1-6-9(2)12(16)17-10(7-11(14)15)8-13(3,4)5/h9-10H,6-8H2,1-5H3
InChi Key IHCPDBBYTYJYIL-UHFFFAOYSA-N
Canonical SMILES CCC(C)C(=O)OC(CC(=O)[O-])C[N+](C)(C)C
Isomeric SMILES CCC(C)C(=O)OC(CC(=O)[O-])C[N+](C)(C)C
Alternate CAS 31023-25-3
PubChem CID 6426901
Molecular Weight 245.32
Beilstein 5946881

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

Flash Point(°F)Not applicable
Flash Point(°C)Not applicable

Safety and Hazards(GHS)

RIDADR NONH for all modes of transport

Related Documents

 SDS

 Specification Sheet

Alternative Products

  1. Isobutyryl-L-carnitine
    Isobutyryl-L-carnitine

    Starting at $266.90

  2. Butyryl-L-carnitine
    Butyryl-L-carnitine

    Starting at $202.90

References

1. T Sakuma,N Sugiyama,T Ichiki,M Kobayashi,Y Wada,D Nohara.  (1991-02-01)  Analysis of acylcarnitines in maternal urine for prenatal diagnosis of glutaric aciduria type 2..  Prenatal diagnosis,  11  ((2)): (77-82).  [PMID:2062823]
2. S Pontremoli,E Melloni,M Michetti,B Sparatore,F Salamino,N Siliprandi,B L Horecker.  (1987-11-13)  Isovalerylcarnitine is a specific activator of calpain of human neutrophils..  Biochemical and biophysical research communications,  148  ((3)): (1189-1195).  [PMID:2825678]
3. D S Millington,C R Roe,D A Maltby,F Inoue.  (1987-01-01)  Endogenous catabolism is the major source of toxic metabolites in isovaleric acidemia..  The Journal of pediatrics,  110  ((1)): (56-60).  [PMID:3794887]
4. R A Chalmers,C R Roe,T E Stacey,C L Hoppel.  (1984-12-01)  Urinary excretion of l-carnitine and acylcarnitines by patients with disorders of organic acid metabolism: evidence for secondary insufficiency of l-carnitine..  Pediatric research,  18  ((12)): (1325-1328).  [PMID:6441143]
5. F Salamino,F Di Lisa,A B Burlina,R Menabŏ,R Barbato,R De Tullio,N Siliprandi.  (1994-08-01)  Involvement of erythrocyte calpain in glycine- and carnitine-treated isovaleric acidemia..  Pediatric research,  36  ((2)): (182-186).  [PMID:7970932]
6. M H Fries,P Rinaldo,E Schmidt-Sommerfeld,E Jurecki,S Packman.  (1996-09-01)  Isovaleric acidemia: response to a leucine load after three weeks of supplementation with glycine, L-carnitine, and combined glycine-carnitine therapy..  The Journal of pediatrics,  129  ((3)): (449-452).  [PMID:8804338]
7. M Fontaine,G Briand,L Vallée,G Ricart,P Degand,P Divry,C Vianey-Saban,J Vamecq.  (1996-08-30)  Acylcarnitine removal in a patient with acyl-CoA beta-oxidation deficiency disorder: effect of L-carnitine therapy and starvation..  Clinica chimica acta; international journal of clinical chemistry,  252  ((2)): (109-122).  [PMID:8853559]
8. C R Roe,S D Cederbaum,D S Roe,R Mardach,A Galindo,L Sweetman.  (1999-01-16)  Isolated isobutyryl-CoA dehydrogenase deficiency: an unrecognized defect in human valine metabolism..  Molecular genetics and metabolism,  65  ((4)): (264-271).  [PMID:9889013]
9. F Ferrara,A Bertelli,M Falchi.  (2005-07-22)  Evaluation of carnitine, acetylcarnitine and isovalerylcarnitine on immune function and apoptosis..  Drugs under experimental and clinical research,  31  ((3)): (109-114).  [PMID:16033249]
10. Judit Bene,Katalin Komlósi,Viktória Havasi,Gábor Talián,Beáta Gasztonyi,Krisztina Horváth,Gyula Mózsik,Béla Hunyady,Béla Melegh,Mária Figler.  (2006-01-28)  Changes of plasma fasting carnitine ester profile in patients with ulcerative colitis..  World journal of gastroenterology,  12  ((1)): (110-113).  [PMID:16440427]
11. Evan L Pannkuk,Evagelia C Laiakis,Kirandeep Gill,Shreyans K Jain,Khyati Y Mehta,Denise Nishita,Kim Bujold,James Bakke,Janet Gahagen,Simon Authier,Polly Chang,Albert J Fornace.  (2019-03-08)  Liquid Chromatography-Mass Spectrometry-Based Metabolomics of Nonhuman Primates after 4 Gy Total Body Radiation Exposure: Global Effects and Targeted Panels..  Journal of proteome research,  18  ((5)): (2260-2269).  [PMID:30843397]
12. David Meierhofer.  (2019-08-16)  Acylcarnitine profiling by low-resolution LC-MS..  PloS one,  14  ((8)): (e0221342-e0221342).  [PMID:31415665]
13. Y Shigematsu,Y Kikawa,M Sudo,H Kanaoka,M Fujioka,M Dan.  (1991-12-16)  Prenatal diagnosis of isovaleric acidemia by fast atom bombardment and tandem mass spectrometry..  Clinica chimica acta; international journal of clinical chemistry,  203  ((2-3)): (369-374).  [PMID:1777996]
14. K Kidouchi,T Niwa,D Nohara,K Asai,N Sugiyama,H Morishita,M Kobayashi,Y Wada.  (1988-04-29)  Urinary acylcarnitines in a patient with neonatal multiple acyl-CoA dehydrogenation deficiency, quantified by a carboxylic acid analyzer with a reversed-phase column..  Clinica chimica acta; international journal of clinical chemistry,  173  ((3)): (263-272).  [PMID:3383426]
15. J E Abdenur,N A Chamoles,A E Guinle,A B Schenone,A N Fuertes.  (1998-10-08)  Diagnosis of isovaleric acidaemia by tandem mass spectrometry: false positive result due to pivaloylcarnitine in a newborn screening programme..  Journal of inherited metabolic disease,  21  ((6)): (624-630).  [PMID:9762597]
16. Dietrich Matern,Miao He,Susan A Berry,Piero Rinaldo,Chester B Whitley,Pia P Madsen,Sandra C van Calcar,Richard C Lussky,Brage S Andresen,Jon A Wolff,Jerry Vockley.  (2003-07-03)  Prospective diagnosis of 2-methylbutyryl-CoA dehydrogenase deficiency in the Hmong population by newborn screening using tandem mass spectrometry..  Pediatrics,  112  ((1 Pt 1)): (74-78).  [PMID:12837870]

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