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20-HETE - ≥98%,a solution in ethanol, high purity , CAS No.79551-86-3, Activator of TRPC6

Moligand™
≥98%
a solution in ethanol

CAS#: 79551-86-3
Formula: C₂₀H₃₂O₃
Molecular Weight: 320.47
MDL number: MFCD00171542
PubChem CID: 5283157

Item Number

H126988

Grouped product items
SKU	Size	Availability	Price	Qty
H126988-25μg	25μg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$567.90
H126988-50μg	50μg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,071.90

View related series

TRPC6 Activator

Basic Description

Synonyms	20-Hete\|79551-86-3\|20-Hydroxyeicosatetraenoic acid\|20-Hydroxy arachidonic acid\|20-Hydroxyarachidonic acid\|(5Z,8Z,11Z,14Z)-20-Hydroxyicosa-5,8,11,14-tetraenoic acid\|20-hydroxy-5,8,11,14-eicosatetraenoic acid\|20-Hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoic acid
Specifications & Purity	Moligand™, ≥98%, a solution in ethanol
Biochemical and Physiological Mechanisms	Description:IC50 Value: N/A20-Hydroxyeicosatetraenoic acid (20-HETE) is a cytochrome P450-derived arachidonic acid metabolite that has been shown to increase smooth muscle contractions and proliferation, stimulate endothelial dysfunction and activation a
Storage Temp	Protected from light,Store at -20°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Action Type	ACTIVATOR
Mechanism of action	Activator of TRPC6
Product Description	20-Hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoic acid 20-HETE is supplied as a solution in ethanol. To change the solvent, simply evaporate the ethanol under a gentle stream of nitrogen and immediately add the solvent of choice. Solvents such as ethanol, DMSO, and dimethyl formamide purged with an inert gas can be used. 20-HETE is miscible in these solvents.

Associated Targets

TRPC6 Tchem Short transient receptor potential channel 6 0 Activities

Discover Target: TRPC6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TRPV1 Tclin Transient receptor potential cation channel subfamily V member 1 0 Activities

Discover Target: TRPV1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PTGS1 Tclin Prostaglandin G/H synthase 1 0 Activities

Discover Target: PTGS1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PTGS2 Tclin Prostaglandin G/H synthase 2 0 Activities

Discover Target: PTGS2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	(5Z,8Z,11Z,14Z)-20-hydroxyicosa-5,8,11,14-tetraenoic acid
INCHI	InChI=1S/C20H32O3/c21-19-17-15-13-11-9-7-5-3-1-2-4-6-8-10-12-14-16-18-20(22)23/h1,3-4,6-7,9-10,12,21H,2,5,8,11,13-19H2,(H,22,23)/b3-1-,6-4-,9-7-,12-10-
InChi Key	NNDIXBJHNLFJJP-DTLRTWKJSA-N
Canonical SMILES	C(CCC=CCC=CCC=CCC=CCCCC(=O)O)CCO
Isomeric SMILES	C(CC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)O)CCO
WGK Germany	1
PubChem CID	5283157
Molecular Weight	320.47

ChEBI

CHEBI:34306

PubChem CID

5283157

CAS Registry No.

79551-86-3

Certificates

Certificate of Analysis(COA)

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1 results found

Lot Number	Certificate Type	Date	Item
H2423158	Certificate of Analysis	May 11, 2024	H126988

Solubility

25°C: DMSO

Sensitivity

Air sensitive；Light sensitive

Flash Point(°F)

57.2 °F

Flash Point(°C)

14 °C

Safety and Hazards(GHS)

Signal	Danger
Hazard Statements	H319:Causes serious eye irritation H225:Highly Flammable liquid and vapor
Precautionary Statements	P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P370+P378:In case of fire: Use ... to extinguish. P210:Keep away from heat, hot surface, sparks, open flames and other ignition sources. - No smoking. P403+P235:Store in a well-ventilated place. Keep cool.
WGK Germany	1

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