Click Here for 5% Off Your First Aladdin Purchase!

(2R,3S)-E1R - 98%, high purity , CAS No.1424832-60-9

  • ≥98%
Item Number
E647122
Grouped product items
SKUSizeAvailabilityPrice Qty
E647122-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$550.90
E647122-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$980.90
E647122-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,500.90
View related series
Neuronal Signaling Sigma Receptor

Basic Description

Specifications & Purity≥98%
Biochemical and Physiological Mechanisms(2R,3S)-E1R (Compound 2c) is an enantiomer of E1R. (2R,3S)-E1R is a sigma-1 receptor positive allosteric modulator ( Sig1R PAM ) for the treatment of cognition/memory disorders.
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

(2R,3S)-E1R (Compound 2c) is an enantiomer of E1R. (2R,3S)-E1R is a sigma-1 receptor positive allosteric modulator ( Sig1R PAM ) for the treatment of cognition/memory disorders.

In Vitro

Sigma-1 receptor plays an important role in neuronal plasticity, a process implicated in the pathophysiology of neuropsychiatric diseases, such as Alzheimer’s disease, major depressive disorders, and schizophrenia. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

Associated Targets

SIGMAR1 Tclin Sigma non-opioid intracellular receptor 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 2-[(2R,3S)-2-methyl-5-oxo-3-phenylpyrrolidin-1-yl]acetamide
INCHI InChI=1S/C13H16N2O2/c1-9-11(10-5-3-2-4-6-10)7-13(17)15(9)8-12(14)16/h2-6,9,11H,7-8H2,1H3,(H2,14,16)/t9-,11-/m1/s1
InChi Key ZTGRWYMPQCQTHD-MWLCHTKSSA-N
Canonical SMILES CC1C(CC(=O)N1CC(=O)N)C2=CC=CC=C2
Isomeric SMILES C[C@@H]1[C@@H](CC(=O)N1CC(=O)N)C2=CC=CC=C2
PubChem CID 71659350
Molecular Weight 232.28

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Chemical and Physical Properties

SolubilityDMSO : 250 mg/mL (1076.29 mM; Need ultrasonic)

Related Documents

Solution Calculators