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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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E647122-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $550.90 | |
E647122-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $980.90 | |
E647122-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,500.90 |
Specifications & Purity | ≥98% |
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Biochemical and Physiological Mechanisms | (2R,3S)-E1R (Compound 2c) is an enantiomer of E1R. (2R,3S)-E1R is a sigma-1 receptor positive allosteric modulator ( Sig1R PAM ) for the treatment of cognition/memory disorders. |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Product Description | (2R,3S)-E1R (Compound 2c) is an enantiomer of E1R. (2R,3S)-E1R is a sigma-1 receptor positive allosteric modulator ( Sig1R PAM ) for the treatment of cognition/memory disorders. In Vitro Sigma-1 receptor plays an important role in neuronal plasticity, a process implicated in the pathophysiology of neuropsychiatric diseases, such as Alzheimer’s disease, major depressive disorders, and schizophrenia. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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IUPAC Name | 2-[(2R,3S)-2-methyl-5-oxo-3-phenylpyrrolidin-1-yl]acetamide |
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INCHI | InChI=1S/C13H16N2O2/c1-9-11(10-5-3-2-4-6-10)7-13(17)15(9)8-12(14)16/h2-6,9,11H,7-8H2,1H3,(H2,14,16)/t9-,11-/m1/s1 |
InChi Key | ZTGRWYMPQCQTHD-MWLCHTKSSA-N |
Canonical SMILES | CC1C(CC(=O)N1CC(=O)N)C2=CC=CC=C2 |
Isomeric SMILES | C[C@@H]1[C@@H](CC(=O)N1CC(=O)N)C2=CC=CC=C2 |
PubChem CID | 71659350 |
Molecular Weight | 232.28 |
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Solubility | DMSO : 250 mg/mL (1076.29 mM; Need ultrasonic) |
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