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(2R,4R)-APDC - ≥98%(HPLC), high purity , CAS No.169209-63-6, Agonist of mGlu 2 receptor;Agonist of mGlu 3 receptor
Highly selective group II agonist
Basic Description Synonyms (2R,4R)-APDC|(2R,4R)-4-aminopyrrolidine-2,4-dicarboxylic acid|169209-63-6|2R,4R-APDC|CHEMBL40086|2,4-Pyrrolidinedicarboxylic acid, 4-amino-, (2R,4R)-|(2R,3R)-APDC|CHEBI:40139|(2R,4R)-4-aminopyrrolidine-2,4-dicarboxylate|2R, 4R-APDC|SCHEMBL158843|GTPL1392| Specifications & Purity Moligand™, ≥98%(HPLC) Biochemical and Physiological Mechanisms A highly selective and relatively potent group II metabotropic glutamate receptor agonist. EC50values are 0.4, 0.4, > 100, > 100, > 300 and > 300μM for human mGlu2, mGlu3, mGlu1, mGlu5, mGlu4and mGlu7receptors respectively. Centrally active following syst Storage Temp Room temperature,Desiccated Shipped In Normal Grade Moligand™ Action Type AGONIST Mechanism of action Agonist of mGlu 2 receptor;Agonist of mGlu 3 receptor
Names and Identifiers IUPAC Name (2R,4R)-4-aminopyrrolidine-2,4-dicarboxylic acid INCHI InChI=1S/C6H10N2O4/c7-6(5(11)12)1-3(4(9)10)8-2-6/h3,8H,1-2,7H2,(H,9,10)(H,11,12)/t3-,6-/m1/s1 InChi Key XZFMJVJDSYRWDQ-AWFVSMACSA-N Canonical SMILES C1C(NCC1(C(=O)O)N)C(=O)O Isomeric SMILES C1[C@@H](NC[C@]1(C(=O)O)N)C(=O)O PubChem CID 5310984 Molecular Weight 174.16
Chemical and Physical Properties Solubility Solvent:water, Max Conc. mg/mL: None, Max Conc. mM: 100
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