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3,3',5-Triiodo-L-thyronine - >98.0%(HPLC), high purity , Thyroid hormone receptor agonist, CAS No.6893-02-3, Thyroid hormone receptor agonist
Basic Description Synonyms liothyronine|triiodothyronine|3,3',5-Triiodo-L-thyronine|6893-02-3|Tresitope|Liothyronin|3,5,3'-triiodothyronine|triothyrone|Liothyroninum|Liotironina|Lyothyronine|3,5,3'-Triiodo-L-thyronine|T3|L-Liothyronine|O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosi Specifications & Purity Moligand™, ≥98%(HPLC) Biochemical and Physiological Mechanisms 3,3′,5-Triiodo-L-thyronine also referred to as O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine or T3 is the biologically active thyroid hormone. In hypothyroidism pateints, triiodothyronine enhances mood and neuropsychological function. The product also Storage Temp Store at -20°C Shipped In Ice chest + Ice pads Grade Moligand™ Action Type AGONIST Mechanism of action Thyroid hormone receptor agonist
Names and Identifiers Pubchem Sid 488179960 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/488179960 IUPAC Name (2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid INCHI InChI=1S/C15H12I3NO4/c16-9-6-8(1-2-13(9)20)23-14-10(17)3-7(4-11(14)18)5-12(19)15(21)22/h1-4,6,12,20H,5,19H2,(H,21,22)/t12-/m0/s1 InChi Key AUYYCJSJGJYCDS-LBPRGKRZSA-N Canonical SMILES C1=CC(=C(C=C1OC2=C(C=C(C=C2I)CC(C(=O)O)N)I)I)O Isomeric SMILES C1=CC(=C(C=C1OC2=C(C=C(C=C2I)C[C@@H](C(=O)O)N)I)I)O RTECS AY6750000 PubChem CID 5920 Molecular Weight 650.98 Reaxy-Rn 2710227
Chemical and Physical Properties Solubility 3,3′,5-Triiodo-L-thyronine dissolves in 4M NH4OH in MeOH at 5 mg/ml to yield a colorless to light yellow, clear to very slightly hazy solution. Sensitivity light sensitive Specific Rotation[α] 23° (C=5,1mol/L HCl:EtOH=1:2) Melt Point(°C) 234-238°C
Safety and Hazards(GHS) Pictogram(s) GHS07 Signal Warning Hazard Statements H315: Causes skin irritation
H319: Causes serious eye irritation
H335: May cause respiratory irritation
Precautionary Statements P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352: IF ON SKIN: wash with plenty of water.
P321: Specific treatment (see ... on this label).
P405: Store locked up.
P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P304+P340: IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P403+P233: Store in a well-ventilated place. Keep container tightly closed.
P362+P364: Take off contaminated clothing and wash it before reuse.
P264+P265: Wash hands [and …] thoroughly after handling. Do not touch eyes.
P337+P317: If eye irritation persists: Get medical help.
P332+P317: If skin irritation occurs: Get medical help.
P319: Get medical help if you feel unwell.
RTECS AY6750000 Reaxy-Rn 2710227 Merck Index 5510
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H2413601