3,5-Di-O-(p-toluyl)-2-deoxy-D-ribofuranosyl chloride - 90%, high purity , CAS No.4330-21-6

Item Number

D121077

Grouped product items
SKU	Size	Availability	Price
D121077-250mg	250mg	In stock	$157.90
D121077-1g	1g	In stock	$483.90
D121077-5g	5g	In stock	$2,175.90
D121077-25g	25g	In stock	$9,791.90
D121077-100g	100g	In stock	$35,250.90

Ribose analog used as an intermediate for synthesis of deoxynucleotides

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Basic Description

Synonyms	Hoffer's chlorosugar\|4330-21-6\|(2R,3S,5R)-5-chloro-2-(((4-methylbenzoyl)oxy)methyl)tetrahydrofuran-3-yl 4-methylbenzoate\|[(2R,3S,5R)-5-chloro-3-(4-methylbenzoyl)oxyoxolan-2-yl]methyl 4-methylbenzoate\|3601-89-6\|2-Deoxy-3,5-di-o-p-toluoyl-ribofuranosyl chlo
Specifications & Purity	≥90%
Biochemical and Physiological Mechanisms	Ribose analog used as an intermediate for synthesis of deoxynucleotides. Reacts with nucleophilic bases to produce beta-D-ribofuranosyl glycosides.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Note	Refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	NSC 148837 is used as a precursor for the synthesis of unnatural β-D-ribofuranosyl containing nucleosides and nucleotides.

Names and Identifiers

IUPAC Name	[(2R,3S,5R)-5-chloro-3-(4-methylbenzoyl)oxyoxolan-2-yl]methyl 4-methylbenzoate
INCHI	InChI=1S/C21H21ClO5/c1-13-3-7-15(8-4-13)20(23)25-12-18-17(11-19(22)26-18)27-21(24)16-9-5-14(2)6-10-16/h3-10,17-19H,11-12H2,1-2H3/t17-,18+,19-/m0/s1
InChi Key	FJHSYOMVMMNQJQ-OTWHNJEPSA-N
Canonical SMILES	CC1=CC=C(C=C1)C(=O)OCC2C(CC(O2)Cl)OC(=O)C3=CC=C(C=C3)C
Isomeric SMILES	CC1=CC=C(C=C1)C(=O)OC[C@@H]2[C@H](C[C@H](O2)Cl)OC(=O)C3=CC=C(C=C3)C
WGK Germany	3
PubChem CID	98571
Molecular Weight	388.84

Certificates

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5 results found

Lot Number	Certificate Type	Date	Item
B2308691	Certificate of Analysis	Dec 01, 2022	D121077
B2308692	Certificate of Analysis	Dec 01, 2022	D121077
B2308706	Certificate of Analysis	Dec 01, 2022	D121077
B2308728	Certificate of Analysis	Dec 01, 2022	D121077
B2308746	Certificate of Analysis	Dec 01, 2022	D121077

Sensitivity

Heat Sensitive

Specific Rotation[α]

77° (C=1,DMF)

Melt Point(°C)

120 °C(dec.)

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	3

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Basic Description