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(3-chlorophenyl) 6-(bromomethyl)-2-oxochromene-3-carboxylate , CAS No.C609256, Inhibitor of kallikrein related peptidase 14;Inhibitor of kallikrein related peptidase 5;Inhibitor of kallikrein related peptidase 7;Inhibitor of ST14 transmembrane serine protease matriptase

  • Moligand™
Item Number
C609256
Grouped product items
SKUSizeAvailabilityPrice Qty
C609256-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,334.90
C609256-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,000.90
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kallikrein related peptidase 14 Inhibitor kallikrein related peptidase 5 Inhibitor kallikrein related peptidase 7 Inhibitor ST14 transmembrane serine protease matriptase Inhibitor

Basic Description

Synonymscompound 4d
GradeMoligand™
Action TypeINHIBITOR
Mechanism of actionInhibitor of kallikrein related peptidase 14;Inhibitor of kallikrein related peptidase 5;Inhibitor of kallikrein related peptidase 7;Inhibitor of ST14 transmembrane serine protease matriptase

Associated Targets

ST14 Tchem Suppressor of tumorigenicity 14 protein 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

KLK7 Tchem Kallikrein-7 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

KLK5 Tchem Kallikrein-5 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

KLK14 Tchem Kallikrein-14 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name (3-chlorophenyl) 6-(bromomethyl)-2-oxochromene-3-carboxylate
INCHI InChI=1S/C17H10BrClO4/c18-9-10-4-5-15-11(6-10)7-14(17(21)23-15)16(20)22-13-3-1-2-12(19)8-13/h1-8H,9H2
InChi Key RNWNTBMGGUARMR-UHFFFAOYSA-N
Canonical SMILES BrCc1ccc2c(c1)cc(c(=O)o2)C(=O)Oc1cccc(c1)Cl
Isomeric SMILES C1=CC(=CC(=C1)Cl)OC(=O)C2=CC3=C(C=CC(=C3)CBr)OC2=O
PubChem CID 90170031

Certificates

Certificate of Analysis(COA)

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Related Documents

 SDS

 Specification Sheet

References

1. Chavanas S, Bodemer C, Rochat A, Hamel-Teillac D, Ali M, Irvine AD, Bonafé JL, Wilkinson J, Taïeb A, Barrandon Y et al..  (2000)  Mutations in SPINK5, encoding a serine protease inhibitor, cause Netherton syndrome..  Nat Genet,  25  (2): (141-2).  [PMID:10835624]
2. Tan X, Soualmia F, Furio L, Renard JF, Kempen I, Qin L, Pagano M, Pirotte B, El Amri C, Hovnanian A et al..  (2015)  Toward the first class of suicide inhibitors of kallikreins involved in skin diseases..  J Med Chem,  58  (2): (598-612).  [PMID:25489658]

Solution Calculators

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