JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.

྾

Home
Applications
Targets
Kinases
TKL:Tyrosine kinase-like
3-[[(cyanoamino)-[(2S)-2-methyl-4-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperazin-1-yl]methylidene]amino]-N-(2-hydroxyethyl)benzamide , CAS No.C608952, Inhibitor of LIM domain kinase 2

3-[[(cyanoamino)-[(2S)-2-methyl-4-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperazin-1-yl]methylidene]amino]-N-(2-hydroxyethyl)benzamide , CAS No.C608952, Inhibitor of LIM domain kinase 2

Item Number

C608952

Grouped product items
SKU	Size	Availability	Price	Qty
C608952-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,334.90
C608952-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,000.90

View related series

Basic Description

Synonyms	compound 22m
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of LIM domain kinase 2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

IUPAC Name	3-[[(cyanoamino)-[(2S)-2-methyl-4-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperazin-1-yl]methylidene]amino]-N-(2-hydroxyethyl)benzamide
INCHI	InChI=1S/C23H27N9O2/c1-15-11-26-20-19(15)21(29-14-28-20)31-7-8-32(16(2)12-31)23(27-13-24)30-18-5-3-4-17(10-18)22(34)25-6-9-33/h3-5,10-11,14,16,33H,6-9,12H2,1-2H3,(H,25,34)(H,27,30)(H,26,28,29)/t16-/m0/s1
InChi Key	BCNLLDVODACBHT-INIZCTEOSA-N
Canonical SMILES	OCCNC(=O)c1cccc(c1)N=C(N1CCN(C[C@@H]1C)c1ncnc2c1c(C)c[nH]2)NC#N
Isomeric SMILES	C[C@H]1CN(CCN1C(=NC2=CC=CC(=C2)C(=O)NCCO)NC#N)C3=NC=NC4=C3C(=CN4)C
PubChem CID	44543082

PubChem CID	44543082
ChEMBL Ligand	CHEMBL571057

Enter Lot Number to search for COA:

1. Harrison BA, Whitlock NA, Voronkov MV, Almstead ZY, Gu KJ, Mabon R, Gardyan M, Hamman BD, Allen J, Gopinathan S et al.. (2009) Novel class of LIM-kinase 2 inhibitors for the treatment of ocular hypertension and associated glaucoma.. J Med Chem, 52 (21): (6515-8). [PMID:19831390]

Determine the necessary mass, volume, or concentration for preparing a solution.

Determine the dilution needed to prepare a stock solution.