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3-Deoxysappanchalcone - 99%, high purity , CAS No.112408-67-0

≥99%

CAS#: 112408-67-0
Formula: C₁₆H₁₄O₄
Molecular Weight: 270.28
PubChem CID: 5319688

Item Number

D650679

Grouped product items
SKU	Size	Availability	Price
D650679-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$166.90
D650679-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$350.90
D650679-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$580.90
D650679-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,180.90

Flavonoids Chalcones Phenols Polyphenols

View related series

Anti-infection Flavonoids Chalcones Phenols Polyphenols Influenza Virus

Basic Description

Synonyms	3-Deoxysappanchalcone\|2'-O-Methylisoliquiritigenin\|112408-67-0\|4,4'-dihydroxy-2'-methoxychalcone\|2'-Methoxyisoliquiritigenin\|51828-10-5\|Isoliquiritigenin 2'-methy ether\|CHEBI:519567\|LHE9JFQ1U8\|CHEMBL253777\|(2E)-1-(4-Hydroxy-2-methoxyphenyl)-3-(4-hydroxyph
Specifications & Purity	≥99%
Biochemical and Physiological Mechanisms	3-Deoxysappanchalcone is a naturally-occurring chalcone compound isolated from Caesalpinia sappan L. (Leguminosae), which possesses anti-allergic, antiviral , anti-inflammatory and antioxidant activities. 3-Deoxysappanchalcone exerts anti-inflammatory ac
Storage Temp	Protected from light,Store at -80°C
Shipped In	Ice chest + Ice pads
Product Description	3-Deoxysappanchalcone is a naturally-occurring chalcone compound isolated from Caesalpinia sappan L. (Leguminosae), which possesses anti-allergic, antiviral, anti-inflammatory and antioxidant activities. 3-Deoxysappanchalcone exerts anti-inflammatory activity via induce heme oxygenase-1 (HO-1) expression by activating the AKT/mTOR pathway in murine macrophages. 3-Deoxysappanchalcone also exhibits anti-influenza virus activity (H3N2, IC 50 = 1.06 μM) Form:Solid IC50& Target:IC50: 1.06 μM (H3N2)

Associated Targets

EGFR Tclin Epidermal growth factor receptor 0 Activities

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SRC Tclin Proto-oncogene tyrosine-protein kinase Src 0 Activities

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FGFR1 Tclin Fibroblast growth factor receptor 1 0 Activities

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FGFR2 Tclin Fibroblast growth factor receptor 2 0 Activities

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MET Tclin Hepatocyte growth factor receptor 0 Activities

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CAPN1 Tchem Calpain-1 catalytic subunit 0 Activities

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KDR Tclin Vascular endothelial growth factor receptor 2 0 Activities

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MAOB Tclin Amine oxidase [flavin-containing] B 0 Activities

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MAOA Tclin Amine oxidase [flavin-containing] A 0 Activities

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KIT Tclin Mast/stem cell growth factor receptor Kit 0 Activities

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Names and Identifiers

IUPAC Name	(E)-1-(4-hydroxy-2-methoxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one
INCHI	InChI=1S/C16H14O4/c1-20-16-10-13(18)7-8-14(16)15(19)9-4-11-2-5-12(17)6-3-11/h2-10,17-18H,1H3/b9-4+
InChi Key	PACBGANPVNHGNP-RUDMXATFSA-N
Canonical SMILES	COC1=C(C=CC(=C1)O)C(=O)C=CC2=CC=C(C=C2)O
Isomeric SMILES	COC1=C(C=CC(=C1)O)C(=O)/C=C/C2=CC=C(C=C2)O
Alternate CAS	51828-10-5,112408-67-0
PubChem CID	5319688
MeSH Entry Terms	3-deoxysappanchalcone
Molecular Weight	270.28

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