Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
SKU | Size | Availability | Price | Qty |
---|---|---|---|---|
H137085-1g | 1g | In stock | $23.90 | |
H137085-5g | 5g | In stock | $89.90 | |
H137085-25g | 25g | In stock | $358.90 | |
H137085-100g | 100g | In stock | $1,289.90 |
Synonyms | 3-HYDROXYPICOLINIC ACID|874-24-8|3-Hydroxypyridine-2-carboxylic acid|3-Hydroxy-2-pyridinecarboxylic acid|3-Hydroxypicolinicacid|3-HPA|2-Pyridinecarboxylic acid, 3-hydroxy-|Pyridinecarboxylic acid, hydroxy-|MFCD00006294|CHEBI:64342|116357-04-1|XV7XP64JR5|C |
---|---|
Specifications & Purity | ≥98% |
Shipped In | Normal |
Product Description | Product Application: 3-Hydroxypyridine-2-carboxylic acid is used as a matrix for nucleotides in MALDI mass spectrometry analyses. |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Pubchem Sid | 488181847 |
---|---|
Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488181847 |
IUPAC Name | 3-hydroxypyridine-2-carboxylic acid |
INCHI | InChI=1S/C6H5NO3/c8-4-2-1-3-7-5(4)6(9)10/h1-3,8H,(H,9,10) |
InChi Key | BRARRAHGNDUELT-UHFFFAOYSA-N |
Canonical SMILES | C1=CC(=C(N=C1)C(=O)O)O |
Isomeric SMILES | C1=CC(=C(N=C1)C(=O)O)O |
WGK Germany | 3 |
PubChem CID | 13401 |
Molecular Weight | 139.11 |
Beilstein | 22(3/4)2134 |
Reaxy-Rn | 118954 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
J2222440 | Certificate of Analysis | Aug 15, 2024 | H137085 |
J2222171 | Certificate of Analysis | Aug 15, 2024 | H137085 |
J2222439 | Certificate of Analysis | Aug 15, 2024 | H137085 |
K2117913 | Certificate of Analysis | Sep 14, 2023 | H137085 |
K2117915 | Certificate of Analysis | Sep 14, 2023 | H137085 |
K2117916 | Certificate of Analysis | Sep 14, 2023 | H137085 |
K2117917 | Certificate of Analysis | Sep 14, 2023 | H137085 |
A2105078 | Certificate of Analysis | Oct 21, 2022 | H137085 |
L2208156 | Certificate of Analysis | Sep 21, 2022 | H137085 |
L2208159 | Certificate of Analysis | Sep 21, 2022 | H137085 |
L2208160 | Certificate of Analysis | Sep 21, 2022 | H137085 |
L2208413 | Certificate of Analysis | Sep 21, 2022 | H137085 |
L2208482 | Certificate of Analysis | Sep 21, 2022 | H137085 |
J2222454 | Certificate of Analysis | Sep 17, 2022 | H137085 |
K1813237 | Certificate of Analysis | Aug 08, 2022 | H137085 |
E1630032 | Certificate of Analysis | Jan 19, 2022 | H137085 |
Solubility | Soluble in water (0.25g in 10ml). |
---|---|
Melt Point(°C) | 213-218 ℃ |
Pictogram(s) | GHS07 |
---|---|
Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
WGK Germany | 3 |
Reaxy-Rn | 118954 |
1. K Curry,D S Magnuson,H McLennan,M J Peet. (1986-05-06) Acridinic acid: a new antagonist of amino acid-induced excitations of central neurones.. Neuroscience letters, 66 ((1)): (101-105). [PMID:3754940] |
2. M S Abu-Bakr. (1993-01-01) Spectrophotometric study of the complexation equilibria of iron(III) with 3-hydroxypicolinic acid and determination of iron in pharmaceutical preparations.. Journal of chemical technology and biotechnology (Oxford, Oxfordshire : 1986), 58 ((3)): (231-236). [PMID:7764310] |
3. J Bai,Y H Liu,D M Lubman,D Siemieniak. (1994-09-01) Matrix-assisted laser desorption/ionization mass spectrometry of restriction enzyme-digested plasmid DNA using an active Nafion substrate.. Rapid communications in mass spectrometry : RCM, 8 ((9)): (687-691). [PMID:7949333] |
4. E Nordhoff,F Kirpekar,M Karas,R Cramer,S Hahner,F Hillenkamp,K Kristiansen,P Roepstroff,A Lezius. (1994-07-11) Comparison of IR- and UV-matrix-assisted laser desorption/ionization mass spectrometry of oligodeoxynucleotides.. Nucleic acids research, 22 ((13)): (2460-2465). [PMID:8041606] |
5. K J Wu,A Steding,C H Becker. (1993-02-01) Matrix-assisted laser desorption time-of-flight mass spectrometry of oligonucleotides using 3-hydroxypicolinic acid as an ultraviolet-sensitive matrix.. Rapid communications in mass spectrometry : RCM, 7 ((2)): (142-146). [PMID:8457722] |
6. J Alper. (1998-04-16) Weighing DNA for fast genetic diagnosis.. Science (New York, N.Y.), 279 ((5359)): (2044-2045). [PMID:9537916] |
7. J M Koomen,D H Russell. (2000-09-06) Ultraviolet/matrix-assisted laser desorption/ionization mass spectrometric characterization of 2,5-dihydroxybenzoic acid-induced reductive hydrogenation of oligonucleotides on cytosine residues.. Journal of mass spectrometry : JMS, 35 ((8)): (1025-1034). [PMID:10973002] |
8. Misaki Nakai,Makoto Obata,Fumi Sekiguchi,Masako Kato,Motoo Shiro,Akio Ichimura,Isamu Kinoshita,Masahiro Mikuriya,Toshifumi Inohara,Kenji Kawabe,Hiromu Sakurai,Chris Orvig,Shigenobu Yano. (2003-12-09) Synthesis and insulinomimetic activities of novel mono- and tetranuclear oxovanadium(IV) complexes with 3-hydroxypyridine-2-carboxylic acid.. Journal of inorganic biochemistry, 98 ((1)): (105-112). [PMID:14659639] |
9. A V Streletskiĭ,A Iu Kozlova,D S Esipov,A L Kaiushin,M D Korosteleva,S E Esipov. (2005-05-14) [Determination of oligonucleotide molecular masses by MS-MALDI].. Bioorganicheskaia khimiia, 31 ((2)): (151-158). [PMID:15889789] |
10. Ningning Liang,Apurba Datta. (2005-11-19) Stereoselective total synthesis of cis- and trans-3-hydroxypipecolic acid.. The Journal of organic chemistry, 70 ((24)): (10182-10185). [PMID:16292869] |
11. Maria Heinrich,Christina Schäffer,Paul Messner,Günter Allmaier. (2009-01-13) Negative ion ultraviolet matrix-assisted laser desorption ionization mass spectrometry and post source decay of glycosyl esters of nucleoside pyrophosphates.. European journal of mass spectrometry (Chichester, England), 14 ((6)): (401-409). [PMID:19136728] |
12. Carole Aimé,Ryuhei Nishiyabu,Ryosuke Gondo,Nobuo Kimizuka. (2010-03-02) Switching on luminescence in nucleotide/lanthanide coordination nanoparticles via synergistic interactions with a cofactor ligand.. Chemistry (Weinheim an der Bergstrasse, Germany), 16 ((12)): (3604-3607). [PMID:20191631] |
13. Jennifer A Jacobsen,Jessica L Fullagar,Melissa T Miller,Seth M Cohen. (2010-12-30) Identifying chelators for metalloprotein inhibitors using a fragment-based approach.. Journal of medicinal chemistry, 54 ((2)): (591-602). [PMID:21189019] |
14. Seth S Bradford,Martin James Ross,Insiya Fidai,James A Cowan. (2014-04-24) Insight into the recognition, binding, and reactivity of catalytic metallodrugs targeting stem loop\u2005IIb of hepatitis\u2005C IRES RNA.. ChemMedChem, 9 ((6)): (1275-1285). [PMID:24756921] |
15. Ewa Radzikowska,Janina Baraniak. (2014-11-05) Synthesis of PS/PO-chimeric oligonucleotides using mixed oxathiaphospholane and phosphoramidite chemistry.. Organic & biomolecular chemistry, 13 ((1)): (269-276). [PMID:25363356] |
16. Indranil Sinha,Célia Fonseca Guerra,Jens Müller. (2015-01-30) A highly stabilizing silver(I)-mediated base pair in parallel-stranded DNA.. Angewandte Chemie (International ed. in English), 54 ((12)): (3603-3606). [PMID:25631645] |
17. Samantha M Sarett,Kameron V Kilchrist,Martina Miteva,Craig L Duvall. (2015-02-03) Conjugation of palmitic acid improves potency and longevity of siRNA delivered via endosomolytic polymer nanoparticles.. Journal of biomedical materials research. Part A, 103 ((9)): (3107-3116). [PMID:25641816] |
18. Saswata Karmakar,Emily M Harcourt,David S Hewings,Florian Scherer,Alexander F Lovejoy,David M Kurtz,Thomas Ehrenschwender,Luzi J Barandun,Caroline Roost,Ash A Alizadeh,Eric T Kool. (2015-08-21) Organocatalytic removal of formaldehyde adducts from RNA and DNA bases.. Nature chemistry, 7 ((9)): (752-758). [PMID:26291948] |
19. Karolyn Barker,Shiva K Rastogi,Jose Dominguez,Travis Cantu,William Brittain,Jennifer Irvin,Tania Betancourt. (2015-11-07) Biodegradable DNA-enabled poly(ethylene glycol) hydrogels prepared by copper-free click chemistry.. Journal of biomaterials science. Polymer edition, 27 ((1)): (22-39). [PMID:26541212] |
20. K Tang,N I Taranenko,S L Allman,C H Chen,L Y Cháng,K B Jacobson. (1994-09-01) Picolinic acid as a matrix for laser mass spectrometry of nucleic acids and proteins.. Rapid communications in mass spectrometry : RCM, 8 ((9)): (673-677). [PMID:7949332] |
21. Y Dai,R M Whittal,L Li,S R Weinberger. (1996-01-01) Accurate mass measurement of oligonucleotides using a time-lag focusing matrix-assisted laser desorption/ionization time-of-flight mass spectrometer.. Rapid communications in mass spectrometry : RCM, 10 ((14)): (1792-1796). [PMID:8953780] |
22. B A Bruenner,T T Yip,T W Hutchens. (1996-01-01) Quantitative analysis of oligonucleotides by matrix-assisted laser desorption/ionization mass spectrometry.. Rapid communications in mass spectrometry : RCM, 10 ((14)): (1797-1801). [PMID:8953781] |
23. Y Kong,Y Zhu,J Y Zhang. (2001-01-03) Ionization mechanism of oligonucleotides in matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.. Rapid communications in mass spectrometry : RCM, 15 ((1)): (57-64). [PMID:11135425] |
24. V B Di Marco,A Tapparo,G G Bombi. (2002-01-05) New possible chelating agents of clinical interest for iron(III): 2-hydroxynicotinic acid and 3-hydroxypicolinic acid. A thermodynamic study.. Annali di chimica, 91 ((9-10)): (595-603). [PMID:11770159] |
25. Lihua Zhou,Huimin Deng,Qinying Deng,Shankai Zhao. (2004-03-31) A mixed matrix of 3-hydroxypicolinic acid and pyrazinecarboxylic acid for matrix-assisted laser desorption/ionization time-of-flight mass spectrometry of oligodeoxynucleotides.. Rapid communications in mass spectrometry : RCM, 18 ((7)): (787-794). [PMID:15052561] |
26. Li-Hua Zhou,Gum-Yong Kang,Kwang Pyo Kim. (2009-06-25) A binary matrix for improved detection of phosphopeptides in matrix-assisted laser desorption/ionization mass spectrometry.. Rapid communications in mass spectrometry : RCM, 23 ((15)): (2264-2272). [PMID:19551845] |
27. Shintaro Kodama,Yukihiro Ueta,Jun Yoshida,Akihiro Nomoto,Shigenobu Yano,Michio Ueshima,Akiya Ogawa. (2009-11-04) Tetranuclear vanadium complex, (VO)(4)(hpic)(4): a recyclable catalyst for oxidation of benzyl alcohols with molecular oxygen.. Dalton transactions (Cambridge, England : 2003), (44) ((44)): (9708-9711). [PMID:19885511] |
28. Wen-Hua Chiou,Gau-Hong Lin,Chih-Wei Liang. (2010-02-09) Facile syntheses of enantiopure 3-hydroxypiperidine derivatives and 3-hydroxypipecolic acids.. The Journal of organic chemistry, 75 ((5)): (1748-1751). [PMID:20136156] |
29. Krešimir Furić,Ivan Kodrin,Boris-Marko Kukovec,Zlatko Mihalić,Zora Popović. (2012-10-30) Vibrational spectroscopic and DFT calculation studies of cobalt(II) complexes with 3-hydroxypicolinic acid.. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 101 (273-282). [PMID:23103469] |
30. Chih-Chi Chu,On Yi Wong,Scott K Silverman. (2014-07-25) A generalizable DNA-catalyzed approach to peptide-nucleic acid conjugation.. Chembiochem : a European journal of chemical biology, 15 ((13)): (1905-1910). [PMID:25056930] |
31. Ieva Kalnciema,Ina Balke,Dace Skrastina,Velta Ose,Andris Zeltins. (2015-09-09) Potato Virus M-Like Nanoparticles: Construction and Characterization.. Molecular biotechnology, 57 ((11-12)): (982-992). [PMID:26346833] |
32. Martin James Ross,Seth S Bradford,J A Cowan. (2015-11-20) Catalytic metallodrugs based on the LaR2C peptide target HCV SLIV IRES RNA.. Dalton transactions (Cambridge, England : 2003), 44 ((48)): (20972-20982). [PMID:26583601] |