3-Isobutyl-1-methylxanthine

Item Number
I755748
Grouped product items
SKUSizeAvailabilityPrice Qty
I755748-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$122.90
I755748-250mg
250mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$198.90
I755748-1g
1g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$556.90

Basic Description

Specifications & PurityBioUltra, ≥99%
Biochemical and Physiological MechanismsThe increase in cAMP level as a result of phosphodiesterase inhibition by IBMX activates PKA, leading to decreased proliferation, increased differentiation, and induction of apoptosis. IBMX inhibits phenylephrine-induced release of 5-hydroxytryptamine fro
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
GradeBioUltra
Product Description3-Isobutyl-1-methylxanthine, an inhibitor of adenosine 3′,5′-cyclic monophosphate phosphodiesterase (cAMP PDE), has been used:

  • for adipogenic differentiation
  • in tissue culture
  • 3T3-L1 preadipocyte differentiation(

Names and Identifiers

IUPAC Name 1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione
INCHI InChI=1S/C10H14N4O2/c1-6(2)4-14-8-7(11-5-12-8)9(15)13(3)10(14)16/h5-6H,4H2,1-3H3,(H,11,12)
InChi Key APIXJSLKIYYUKG-UHFFFAOYSA-N
Canonical SMILES CC(C)CN1C2=C(C(=O)N(C1=O)C)NC=N2
Isomeric SMILES CC(C)CN1C2=C(C(=O)N(C1=O)C)NC=N2
WGK Germany 3
RTECS ZD8500000
PubChem CID 3758
Molecular Weight 222.24
Beilstein 247859

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilityDMSO: soluble 1 M (with gentle warming)
Melt Point(°C)200-203°C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H302:Harmful if swallowed

Precautionary Statements

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P270:Do not eat, drink or smoke when using this product.

P330:Rinse mouth.

P301+P317:IF SWALLOWED: Get medical help.

WGK Germany 3
RTECS ZD8500000

Related Documents

Solution Calculators