3-Maleimido-propionic NHS ester contains a maleimide group and an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
1.Qiao Chen, Xinmei Duan, Yao Yu, Rongrong Ni, Guojing Song, Xu Yang, Li Zhu, Yuan Zhong, Kun Zhang, Kai Qu, Xian Qin, Wei Wu. (2023) Target Functionalized Carbon Dot Nanozymes with Dual-Model Photoacoustic and Fluorescence Imaging for Visual Therapy in Atherosclerosis. Advanced Science, (2307441). [PMID:38145362][10.1002/advs.202307441]
2.Qingqing Meng, Aiping Wang, Hongchen Hua, Ying Jiang, Yiyun Wang, Hongjie Mu, Zimei Wu, Kaoxiang Sun. (2023) Intranasal delivery of Huperzine A to the brain using lactoferrin-conjugated N-trimethylated chitosan surface-modified PLGA nanoparticles for treatment of Alzheimer’s disease. International Journal of Nanomedicine, [PMID:29440896][10.2147/IJN.S151474]
References
1.Qiao Chen, Xinmei Duan, Yao Yu, Rongrong Ni, Guojing Song, Xu Yang, Li Zhu, Yuan Zhong, Kun Zhang, Kai Qu, Xian Qin, Wei Wu. (2023) Target Functionalized Carbon Dot Nanozymes with Dual-Model Photoacoustic and Fluorescence Imaging for Visual Therapy in Atherosclerosis. Advanced Science, (2307441). [PMID:38145362][10.1002/advs.202307441]
2.Qingqing Meng, Aiping Wang, Hongchen Hua, Ying Jiang, Yiyun Wang, Hongjie Mu, Zimei Wu, Kaoxiang Sun. (2023) Intranasal delivery of Huperzine A to the brain using lactoferrin-conjugated N-trimethylated chitosan surface-modified PLGA nanoparticles for treatment of Alzheimer’s disease. International Journal of Nanomedicine, [PMID:29440896][10.2147/IJN.S151474]
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