The store will not work correctly when cookies are disabled.
JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.
3-MATIDA - ≥99%, high purity , CAS No.518357-51-2, Antagonist of mGlu 1 receptor
a potent mGluR-1 antagonist
Basic Description Synonyms 3-MATIDA|518357-51-2|5-[amino(carboxy)methyl]-4-methylthiophene-2-carboxylic acid|5-(Amino(carboxy)methyl)-4-methylthiophene-2-carboxylic acid|alpha-amino-5-carboxy-3-methyl-2-thiopheneacetic acid|SCHEMBL658044|GTPL3396|CHEMBL1322301|CHEBI:93911|DTXSID404 Specifications & Purity Moligand™, ≥99% Storage Temp Store at 2-8°C Shipped In Wet ice Grade Moligand™ Action Type ANTAGONIST Mechanism of action Antagonist of mGlu 1 receptor Product Description 3-MATIDA is a potent metabotropic glutamate receptor 1(mGluR-1) antagonist (IC|50|= 6.3 μM at rat mGluR-1a). Displays ≥ 40-fold selectivity over other receptors: mGluR-5, mGluR-2, mGluR-4 (mGluR-4a) (IC|50|> 300 μM), NMDA and GluR (AMPA) (IC|50|= 250 μM). 3-MATIDA has been found to act as a neuroprotectant in cultured murine cortical cells and rat hippocampal slice cultures|in vitro|.
Names and Identifiers IUPAC Name 5-[amino(carboxy)methyl]-4-methylthiophene-2-carboxylic acid INCHI InChI=1S/C8H9NO4S/c1-3-2-4(7(10)11)14-6(3)5(9)8(12)13/h2,5H,9H2,1H3,(H,10,11)(H,12,13) InChi Key KOMWRBFEDDEWEP-UHFFFAOYSA-N Canonical SMILES CC1=C(SC(=C1)C(=O)O)C(C(=O)O)N Isomeric SMILES CC1=C(SC(=C1)C(=O)O)C(C(=O)O)N RTECS XM7572000 PubChem CID 10398360
Chemical and Physical Properties Solubility Soluble in 1eq. NaOH (100 mM), and DMSO (50 mM). Refractive Index n20D1.65 (Predicted)
Solution Calculators Molarity Calculator Determine the necessary mass, volume, or concentration for preparing a solution.
Dilution Calculator Determine the dilution needed to prepare a stock solution.
Reconstitution Calculator
