Click Here for 5% Off Your First Aladdin Purchase!

3-naphthalen-2-yl-5-piperidin-4-yl-1,2,4-oxadiazole , CAS No.N609171, Antagonist of Farnesoid X receptor

  • Moligand™
Item Number
N609171
Grouped product items
SKUSizeAvailabilityPrice Qty
N609171-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,334.90
N609171-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,000.90
View related series
Farnesoid X receptor Antagonist

Basic Description

Synonymscompound 3f
Specifications & PurityMoligand™
GradeMoligand™
Action TypeANTAGONIST
Mechanism of actionAntagonist of Farnesoid X receptor

Associated Targets

NR1H2 Tchem Oxysterols receptor LXR-beta 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

NR1H3 Tchem Oxysterols receptor LXR-alpha 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

NR1H4 Tclin Bile acid receptor 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

NR1I2 Tchem Nuclear receptor subfamily 1 group I member 2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PPARG Tclin Peroxisome proliferator-activated receptor gamma 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

INCHI InChI=1S/C17H17N3O/c1-2-4-14-11-15(6-5-12(14)3-1)16-19-17(21-20-16)13-7-9-18-10-8-13/h1-6,11,13,18H,7-10H2
InChi Key PPCNFLPYHQIYHP-UHFFFAOYSA-N
Canonical SMILES N1CCC(CC1)c1onc(n1)c1ccc2c(c1)cccc2
Isomeric SMILES C1CNCCC1C2=NC(=NO2)C3=CC4=CC=CC=C4C=C3
PubChem CID 62715191

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Related Documents

References

1. Festa C, Finamore C, Marchianò S, Di Leva FS, Carino A, Monti MC, Del Gaudio F, Ceccacci S, Limongelli V, Zampella A et al..  (2019)  Investigation around the Oxadiazole Core in the Discovery of a New Chemotype of Potent and Selective FXR Antagonists..  ACS Med Chem Lett,  10  (4): (504-510).  [PMID:30996787]

Solution Calculators