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(3Z)-5-(2-chloroacetyl)-3-(1H-pyrrol-2-ylmethylidene)-1H-indol-2-one , CAS No.Z609077, Inhibitor of NIMA related kinase 2

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(3Z)-5-(2-chloroacetyl)-3-(1H-pyrrol-2-ylmethylidene)-1H-indol-2-one , CAS No.Z609077, Inhibitor of NIMA related kinase 2

Moligand™

PubChem CID: 16662746

Item Number

Z609077

Grouped product items
SKU	Size	Availability	Price	Qty
Z609077-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,334.90
Z609077-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,000.90

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NIMA related kinase 2 Inhibitor

Basic Description

Synonyms	compound 2
Specifications & Purity	Moligand™
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of NIMA related kinase 2

Associated Targets

CDK1 Tchem Cyclin-dependent kinase 1 0 Activities

Discover Target: CDK1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NEK2 Tchem Serine/threonine-protein kinase Nek2 1 Activities

Discover Target: NEK2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	(3Z)-5-(2-chloroacetyl)-3-(1H-pyrrol-2-ylmethylidene)-1H-indol-2-one
INCHI	InChI=1S/C15H11ClN2O2/c16-8-14(19)9-3-4-13-11(6-9)12(15(20)18-13)7-10-2-1-5-17-10/h1-7,17H,8H2,(H,18,20)/b12-7-
InChi Key	SEPHEVMRHYRRLS-GHXNOFRVSA-N
Canonical SMILES	ClCC(=O)c1ccc2c(c1)/C(=C/c1ccc[nH]1)/C(=O)N2
Isomeric SMILES	C1=CNC(=C1)/C=C\2/C3=C(C=CC(=C3)C(=O)CCl)NC2=O
PubChem CID	16662746

Database links

ChEMBL Ligand	CHEMBL1802381
PubChem CID	16662746
BindingDB Ligand	50418829

Certificates

Certificate of Analysis(COA)

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References

1. Henise JC, Taunton J. (2011) Irreversible Nek2 kinase inhibitors with cellular activity.. J Med Chem, 54 (12): (4133-46). [PMID:21627121]

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