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4-(2,5-dioxo-2H-pyrrol-1(5H)-yl)butanoic acid - 96%, high purity , CAS No.57078-98-5
Basic Description Synonyms 4-Maleimidobutyric acid|57078-98-5|4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)butanoic acid|4-(2,5-dioxo-2H-pyrrol-1(5H)-yl)butanoic acid|gamma-Maleimidobutyric acid|Maleimide-(CH2)3-COOH|1H-Pyrrole-1-butanoic acid, 2,5-dihydro-2,5-dioxo-|N-(3-Carboxypropyl) Specifications & Purity 96% Storage Temp Store at -20°C Shipped In Ice chest + Ice pads Product Description 4-(2,5-dioxo-2H-pyrrol-1(5H)-yl)butanoic acid contains a maleimide group and a terminal carboxylic acid. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
Names and Identifiers IUPAC Name 4-(2,5-dioxopyrrol-1-yl)butanoic acid INCHI InChI=1S/C8H9NO4/c10-6-3-4-7(11)9(6)5-1-2-8(12)13/h3-4H,1-2,5H2,(H,12,13) InChi Key NCPQROHLJFARLL-UHFFFAOYSA-N Canonical SMILES C1=CC(=O)N(C1=O)CCCC(=O)O Isomeric SMILES C1=CC(=O)N(C1=O)CCCC(=O)O WGK Germany 3 PubChem CID 3404904 Molecular Weight 183.16 Beilstein 1455876 Reaxy-Rn 1455876
Chemical and Physical Properties Safety and Hazards(GHS) Pictogram(s) GHS07 Signal Warning Hazard Statements H315: Causes skin irritation
H319: Causes serious eye irritation
H335: May cause respiratory irritation
Precautionary Statements P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352: IF ON SKIN: wash with plenty of water.
P321: Specific treatment (see ... on this label).
P405: Store locked up.
P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P304+P340: IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P403+P233: Store in a well-ventilated place. Keep container tightly closed.
P362+P364: Take off contaminated clothing and wash it before reuse.
P264+P265: Wash hands [and …] thoroughly after handling. Do not touch eyes.
P337+P317: If eye irritation persists: Get medical help.
P332+P317: If skin irritation occurs: Get medical help.
P319: Get medical help if you feel unwell.
WGK Germany 3 Reaxy-Rn 1455876
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