Determine the necessary mass, volume, or concentration for preparing a solution.
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SKU | Size | Availability | Price | Qty |
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D105859-250mg | 250mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $38.90 | |
D105859-500mg | 500mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $68.90 | |
D105859-1g | 1g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $123.90 | |
D105859-5g | 5g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $554.90 |
Antibacterial and anti-inflammatory agent
Synonyms | dapsone|80-08-0|4,4'-Sulfonyldianiline|4,4'-Diaminodiphenyl sulfone|Diaphenylsulfone|4,4'-Diaminodiphenylsulfone|Dapson|4-Aminophenyl sulfone|Novophone|DADPS|Diaphenylsulfon|Dapsonum|Diphenasone|Sulphadione|Aczone|Sulfona|Bis(4-aminophenyl) sulfone|p-Amin |
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Specifications & Purity | Moligand™, analytical standard |
Biochemical and Physiological Mechanisms | Antibacterial and anti-inflammatory agent. Neuroprotective and anti-apoptotic effects. |
Shipped In | Normal |
Grade | analytical standard, Moligand™ |
Action Type | AGONIST |
Mechanism of action | Agonist of TAS2R40 |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
ALogP | 1 |
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IUPAC Name | 4-(4-aminophenyl)sulfonylaniline |
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INCHI | InChI=1S/C12H12N2O2S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8H,13-14H2 |
InChi Key | MQJKPEGWNLWLTK-UHFFFAOYSA-N |
Canonical SMILES | C1=CC(=CC=C1N)S(=O)(=O)C2=CC=C(C=C2)N |
Isomeric SMILES | C1=CC(=CC=C1N)S(=O)(=O)C2=CC=C(C=C2)N |
WGK Germany | 1 |
RTECS | BY8925000 |
PubChem CID | 2955 |
Molecular Weight | 248.3 |
Beilstein | 788055 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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C2304455 | Certificate of Analysis | Dec 21, 2022 | D105859 |
C2304463 | Certificate of Analysis | Dec 21, 2022 | D105859 |
C2304469 | Certificate of Analysis | Dec 21, 2022 | D105859 |
C2304475 | Certificate of Analysis | Dec 21, 2022 | D105859 |
G1205046 | Certificate of Analysis | Nov 10, 2022 | D105859 |
Sensitivity | Moisture sensitive. |
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Melt Point(°C) | 173-178°C |
Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H302:Harmful if swallowed |
Precautionary Statements | P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help. |
WGK Germany | 1 |
RTECS | BY8925000 |
Merck Index | 2822 |
1. Petersen E. (2004) Malaria chemoprophylaxis: when should we use it and what are the options?. Expert Rev Anti Infect Ther, 2 (1): (119-32). [PMID:15482177] |
2. Zhang Y, Meshnick SR. (1991) Inhibition of Plasmodium falciparum dihydropteroate synthetase and growth in vitro by sulfa drugs.. Antimicrob Agents Chemother, 35 (2): (267-71). [PMID:2024960] |
3. Luzzatto L. (2010) The rise and fall of the antimalarial Lapdap: a lesson in pharmacogenetics.. Lancet, 376 (9742): (739-41). [PMID:20599264] |
4. Barr J. (2011) A short history of dapsone, or an alternative model of drug development.. J Hist Med Allied Sci, 66 (4): (425-67). [PMID:20966036] |
5. Queener SF. (1995) New drug developments for opportunistic infections in immunosuppressed patients: Pneumocystis carinii.. J Med Chem, 38 (24): (4739-59). [PMID:7490723] |