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4,4′-(Hexafluoroisopropylidene)bis(p-phenyleneoxy)dianiline - 97%, high purity , CAS No.69563-88-8, Activator of K 2P10.1;Activator of K 2P2.1

  • ≥97%
Item Number
H102221
Grouped product items
SKUSizeAvailabilityPrice Qty
H102221-5g
5g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$30.90
H102221-25g
25g
Available within 1-2 weeks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
$106.90
H102221-100g
100g
In stock
$299.90
H102221-500g
500g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$999.90
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K2P2.1 (TREK-1) and K2P10.1 (TREK-2) channel activator

View related series
Diamine monomer Polymer / polymer reagent

Basic Description

Synonyms69563-88-8|2,2-Bis[4-(4-aminophenoxy)phenyl]hexafluoropropane|GI-530159|4,4'-(((Perfluoropropane-2,2-diyl)bis(4,1-phenylene))bis(oxy))dianiline|GI 530159|2,2-Bis(4-(4-aminophenoxy)phenyl)hexafluoropropane|2,2-Bis(4-[4-aminophenoxy]phenyl)hexafluoropropane
Specifications & Purity97%
Shipped InNormal
Action TypeACTIVATOR
Mechanism of actionActivator of K 2P10.1;Activator of K 2P2.1

Associated Targets

KCNK2 Tclin Potassium channel subfamily K member 2 2 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

KCNK10 Tclin Potassium channel subfamily K member 10 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

Pubchem Sid488186850
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488186850
IUPAC Name 4-[4-[2-[4-(4-aminophenoxy)phenyl]-1,1,1,3,3,3-hexafluoropropan-2-yl]phenoxy]aniline
INCHI InChI=1S/C27H20F6N2O2/c28-26(29,30)25(27(31,32)33,17-1-9-21(10-2-17)36-23-13-5-19(34)6-14-23)18-3-11-22(12-4-18)37-24-15-7-20(35)8-16-24/h1-16H,34-35H2
InChi Key HHLMWQDRYZAENA-UHFFFAOYSA-N
Canonical SMILES C1=CC(=CC=C1C(C2=CC=C(C=C2)OC3=CC=C(C=C3)N)(C(F)(F)F)C(F)(F)F)OC4=CC=C(C=C4)N
Isomeric SMILES C1=CC(=CC=C1C(C2=CC=C(C=C2)OC3=CC=C(C=C3)N)(C(F)(F)F)C(F)(F)F)OC4=CC=C(C=C4)N
WGK Germany 3
RTECS CY1213000
PubChem CID 94652
Molecular Weight 518.45
Reaxy-Rn 8879443

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

19 results found

Lot NumberCertificate TypeDateItem
L1211053Certificate of AnalysisAug 12, 2024 H102221
G2425613Certificate of AnalysisJul 05, 2024 H102221
G2425612Certificate of AnalysisJul 05, 2024 H102221
G2425611Certificate of AnalysisJul 05, 2024 H102221
E2417200Certificate of AnalysisMay 09, 2024 H102221
E2417203Certificate of AnalysisMay 09, 2024 H102221
E2417202Certificate of AnalysisMay 09, 2024 H102221
E2417201Certificate of AnalysisMay 09, 2024 H102221
D2418484Certificate of AnalysisApr 07, 2024 H102221
D2418476Certificate of AnalysisApr 07, 2024 H102221
D2418473Certificate of AnalysisApr 07, 2024 H102221
A2410205Certificate of AnalysisJan 02, 2024 H102221
A2410227Certificate of AnalysisJan 02, 2024 H102221
A2410226Certificate of AnalysisJan 02, 2024 H102221
A2410225Certificate of AnalysisJan 02, 2024 H102221
A2410224Certificate of AnalysisJan 02, 2024 H102221
A2410206Certificate of AnalysisJan 02, 2024 H102221
I2227327Certificate of AnalysisJul 24, 2022 H102221
I2227329Certificate of AnalysisJul 24, 2022 H102221

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Chemical and Physical Properties

SolubilityInsoluble in water, soluble in methanol
Melt Point(°C)159-163°C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H302:Harmful if swallowed

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P270:Do not eat, drink or smoke when using this product.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P330:Rinse mouth.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P301+P317:IF SWALLOWED: Get medical help.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 3
RTECS CY1213000
Reaxy-Rn 8879443

Related Documents

 SDS

 Specification Sheet

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References

1. Loucif AJC, Saintot PP, Liu J, Antonio BM, Zellmer SG, Yoger K, Veale EL, Wilbrey A, Omoto K, Cao L et al..  (2018)  GI-530159, a novel, selective, mechanosensitive two-pore-domain potassium (K2P ) channel opener, reduces rat dorsal root ganglion neuron excitability..  Br J Pharmacol,  175  (12): (2272-2283).  [PMID:29150838]

Solution Calculators

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