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4-Aminosalicylic acid - 10mM in DMSO, high purity , CAS No.65-49-6
Competitive pteridine synthetase inhibitor
Basic Description
Synonyms | 4-Aminosalicylic acid|65-49-6|4-Amino-2-hydroxybenzoic acid|Aminosalicylic acid|P-AMINOSALICYLIC ACID|Rezipas|Para-aminosalicylic acid|Aminopar|Pamisyl|Parasal|Paser|Parasalindon|Deapasil|Apacil|Gabbropas|Paramycin|Parasalicil|Pasnodia|Aminox|Benzoic acid |
Specifications & Purity | 10mM in DMSO |
Biochemical and Physiological Mechanisms | Competitive pteridine synthetase inhibitor. Shows antituberculosis activity. Inhibits NF-κB and folic acid synthesis. Orally active. |
Storage Temp | Store at -80°C |
Shipped In | Ice chest + Ice pads |
Product Description | 4-Aminosalicylic acid is an inhibitor of NF κ B. A antibacterial capable of inhibiting the growth of Mycobacterium tuberculosis |
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Names and Identifiers
IUPAC Name | 4-amino-2-hydroxybenzoic acid |
INCHI | InChI=1S/C7H7NO3/c8-4-1-2-5(7(10)11)6(9)3-4/h1-3,9H,8H2,(H,10,11) |
InChi Key | WUBBRNOQWQTFEX-UHFFFAOYSA-N |
Canonical SMILES | C1=CC(=C(C=C1N)O)C(=O)O |
Isomeric SMILES | C1=CC(=C(C=C1N)O)C(=O)O |
WGK Germany | 2 |
RTECS | VO1225000 |
PubChem CID | 4649 |
Molecular Weight | 153.14 |
Beilstein | 473071 |
Reaxy-Rn | 473071 |
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Chemical and Physical Properties
Sensitivity | Light and Air sensitive |
Melt Point(°C) | 150-151°C |
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Safety and Hazards(GHS)
Pictogram(s) | GHS07 |
Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
WGK Germany | 2 |
RTECS | VO1225000 |
Reaxy-Rn | 473071 |
Merck Index | 477 |
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