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Transmembrane Transporters
Voltage-gated ion channels
Transient Receptor Potential channels (TRP)
4-chloro-2-[[2-(2-chlorophenoxy)acetyl]amino]benzoic acid , CAS No.C609353, Channel blocker of TRPM4;Gating inhibitor of TRPM4

4-chloro-2-[[2-(2-chlorophenoxy)acetyl]amino]benzoic acid , CAS No.C609353, Channel blocker of TRPM4;Gating inhibitor of TRPM4

Item Number

C609353

Grouped product items
SKU	Size	Availability	Price	Qty
C609353-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,334.90
C609353-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,001.90

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Basic Description

Synonyms	CBA;compound 5
Grade	Moligand™
Action Type	CHANNEL BLOCKER, GATING INHIBITOR
Mechanism of action	Channel blocker of TRPM4;Gating inhibitor of TRPM4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

IUPAC Name	4-chloro-2-[[2-(2-chlorophenoxy)acetyl]amino]benzoic acid
INCHI	InChI=1S/C15H11Cl2NO4/c16-9-5-6-10(15(20)21)12(7-9)18-14(19)8-22-13-4-2-1-3-11(13)17/h1-7H,8H2,(H,18,19)(H,20,21)
InChi Key	CVQCJPCMPGKEDH-UHFFFAOYSA-N
Canonical SMILES	O=C(Nc1cc(Cl)ccc1C(=O)O)COc1ccccc1Cl
Isomeric SMILES	C1=CC=C(C(=C1)OCC(=O)NC2=C(C=CC(=C2)Cl)C(=O)O)Cl
PubChem CID	2264067

PubChem CID	2264067

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1. Ozhathil LC, Delalande C, Bianchi B, Nemeth G, Kappel S, Thomet U, Ross-Kaschitza D, Simonin C, Rubin M, Gertsch J et al.. (2018) Identification of potent and selective small molecule inhibitors of the cation channel TRPM4.. Br J Pharmacol, 175 (12): (2504-2519). [PMID:29579323]

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