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4-Hydroxy-3-methoxycinnamaldehyde - 98%, high purity , CAS No.458-36-6

  • ≥98%
Item Number
H473328
Grouped product items
SKUSizeAvailabilityPrice Qty
H473328-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$16.90
H473328-250mg
250mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$32.90
H473328-1g
1g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$89.90
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Basic Description

SynonymsConiferaldehyde|Coniferyl aldehyde|4-HYDROXY-3-METHOXYCINNAMALDEHYDE|458-36-6|20649-42-7|Ferulaldehyde|Ferulyl aldehyde|3-(4-Hydroxy-3-methoxyphenyl)acrylaldehyde|coniferylaldehyde|p-Coniferaldehyde|(E)-Ferulaldehyde|3-Methoxy-4-hydroxycinnamaldehyde|tran
Specifications & Purity≥98%
Storage TempStore at 2-8°C,Protected from light,Argon charged
Shipped InWet ice
Product Description

4-Hydroxy-3-methoxycinnamaldehyde is an isoflavonoid. It has been isolated from the insecticidally active hot dichloromethane extract of heartwood ofGliricidia sepium, seed kernels ofMelia azedarachL and barks ofCinnamomum cebuense.4-Hydroxy-3-methoxycinnamaldehyde is suitable for use in a study to investigate the antioxidant and antiradical activities of ferulates using a β-carotene-linoleate model system and a DPPH radical scavenging assay, respectively.

Coniferaldehyde (Ferulaldehyde) is an effective inducer of heme oxygenase-1 (HO-1) and has anti-inflammatory effects. In RAW264.7 macrophages, Coniferaldehyde inhibited LPS-induced apoptosis through a PKCα/βII/Nrf-2/HO-1 dependent pathway

Associated Targets

HSF1 Tchem Heat shock factor protein 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

XDH Tclin Xanthine dehydrogenase/oxidase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enal
INCHI InChI=1S/C10H10O3/c1-13-10-7-8(3-2-6-11)4-5-9(10)12/h2-7,12H,1H3/b3-2+
InChi Key DKZBBWMURDFHNE-NSCUHMNNSA-N
Canonical SMILES COC1=C(C=CC(=C1)C=CC=O)O
Isomeric SMILES COC1=C(C=CC(=C1)/C=C/C=O)O
PubChem CID 5280536
Molecular Weight 178.18

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

9 results found

Lot NumberCertificate TypeDateItem
A2419414Certificate of AnalysisDec 27, 2023 H473328
A2419415Certificate of AnalysisDec 27, 2023 H473328
A2419419Certificate of AnalysisDec 27, 2023 H473328
A2419420Certificate of AnalysisDec 27, 2023 H473328
A2419421Certificate of AnalysisDec 27, 2023 H473328
A2419425Certificate of AnalysisDec 27, 2023 H473328
L2320196Certificate of AnalysisDec 13, 2023 H473328
L2320197Certificate of AnalysisDec 13, 2023 H473328
L2320198Certificate of AnalysisDec 13, 2023 H473328

Chemical and Physical Properties

SensitivityAir Sensitive，Light Sensitive
Boil Point(°C)175 °C/5 mmHg
Melt Point(°C)80-82℃

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

Related Documents

 SDS

 Specification Sheet

Alternative Products

  1. 4-Hydroxy-3-methoxycinnamaldehyde - Analysis standard, used for , CAS No. 458-36-6, by Aladdin Scientific
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  2. 4-Hydroxy-3-methoxycinnamaldehyde - 10mM in DMSO, used for , CAS No. 458-36-6, by Aladdin Scientific
    4-Hydroxy-3-methoxycinnamaldehyde

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  3. 2-methoxycinnamaldehyde - 10mM in DMSO, used for , CAS No. 1504-74-1(DMSO), by Aladdin Scientific
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  4. 4-Acetoxy-3-methoxycinnamaldehyde
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  5. trans-4-Methoxycinnamaldehyde
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  6. 2-methoxycinnamaldehyde - 98%, used for , CAS No. 1504-74-1, by Aladdin Scientific
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References

1. María C Carpinella,Carlos G Ferrayoli,Sara M Palacios.  (2005-04-14)  Antifungal synergistic effect of scopoletin, a hydroxycoumarin isolated from Melia azedarach L. fruits..  Journal of agricultural and food chemistry,  53  ((8)): (2922-2927).  [PMID:15826040]
2. M Lisa Manier,Michelle L Reyzer,Anne Goh,Veronique Dartois,Laura E Via,Clifton E Barry,Richard M Caprioli.  (2011-09-29)  Reagent precoated targets for rapid in-tissue derivatization of the anti-tuberculosis drug isoniazid followed by MALDI imaging mass spectrometry..  Journal of the American Society for Mass Spectrometry,  22  ((8)): (1409-1419).  [PMID:21953196]
3. Consolacion Y Ragasa,Dinah L Espineli,Esperanza Maribel G Agoo,Ramon S Del Fierro.  (2013-06-04)  Chemical constituents of Cinnamomum cebuense..  Chinese journal of natural medicines,  11  ((3)): (264-268).  [PMID:23725839]
4. M Lisa Manier,Jeffrey M Spraggins,Michelle L Reyzer,Jeremy L Norris,Richard M Caprioli.  (2014-07-22)  A derivatization and validation strategy for determining the spatial localization of endogenous amine metabolites in tissues using MALDI imaging mass spectrometry..  Journal of mass spectrometry : JMS,  49  ((8)): (665-673).  [PMID:25044893]
5. Eugene Fletcher,Kai Gao,Kevin Mercurio,Mariam Ali,Kristin Baetz.  (2018-11-25)  Yeast chemogenomic screen identifies distinct metabolic pathways required to tolerate exposure to phenolic fermentation inhibitors ferulic acid, 4-hydroxybenzoic acid and coniferyl aldehyde..  Metabolic engineering,  52  (98-109).  [PMID:30471359]
6. Katarzyna Grecka,Piotr M Kuś,Piotr Okińczyc,Randy W Worobo,Justyna Walkusz,Piotr Szweda.  (2019-05-07)  The Anti-Staphylococcal Potential of Ethanolic Polish Propolis Extracts..  Molecules (Basel, Switzerland),  24  ((9)):   [PMID:31058881]
7. Peter Bock,Notburga Gierlinger.  (2019-07-03)  Infrared and Raman spectra of lignin substructures: Coniferyl alcohol, abietin, and coniferyl aldehyde..  Journal of Raman spectroscopy : JRS,  50  ((6)): (778-792).  [PMID:31263319]
8. Leonard Blaschek,Antoine Champagne,Charilaos Dimotakis,Nuoendagula,Raphaël Decou,Shojiro Hishiyama,Susanne Kratzer,Shinya Kajita,Edouard Pesquet.  (2020-03-21)  Cellular and Genetic Regulation of Coniferaldehyde Incorporation in Lignin of Herbaceous and Woody Plants by Quantitative Wiesner Staining..  Frontiers in plant science,  11  (109-109).  [PMID:32194582]
9. Masanobu Yamamoto,Leonard Blaschek,Elena Subbotina,Shinya Kajita,Edouard Pesquet.  (2020-07-22)  Importance of Lignin Coniferaldehyde Residues for Plant Properties and Sustainable Uses..  ChemSusChem,  13  ((17)): (4400-4408).  [PMID:32692480]
10. Seikwan Oh,Soyong Jang,Donghyun Kim,Inn-Oc Han,Jae-Chul Jung.  (2006-07-13)  Synthesis and evaluation of biological properties of benzylideneacetophenone derivatives..  Archives of pharmacal research,  29  ((6)): (469-475).  [PMID:16833013]
11. Yi Sun,Yifeng Wu,Yu Zhao,Xiaojuan Han,Hongxiang Lou,Aixia Cheng.  (2013-06-19)  Molecular cloning and biochemical characterization of two cinnamyl alcohol dehydrogenases from a liverwort Plagiochasma appendiculatum..  Plant physiology and biochemistry : PPB,  70  (133-141).  [PMID:23774375]
12. Lei Xu,Fei Lao,Zhenzhen Xu,Xue Wang,Fang Chen,Xiaojun Liao,Ailiang Chen,Shuming Yang.  (2019-03-05)  Use of liquid chromatography quadrupole time-of-flight mass spectrometry and metabolomic approach to discriminate coffee brewed by different methods..  Food chemistry,  286  (106-112).  [PMID:30827582]
13. Linda Volpp,Vladimír Ferianec,Miriam Ježovičová,Zdeňka Ďuračková,Oliver Scherf-Clavel,Petra Högger.  (2020-03-17)  Constituents and Metabolites of a French Oak Wood Extract (Robuvit®) in Serum and Blood Cell Samples of Women Undergoing Hysterectomy..  Frontiers in pharmacology,  11  (74-74).  [PMID:32174825]

Solution Calculators

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