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4-Hydroxy Valsartan (Mixture of Diastereomers) , CAS No.188259-69-0

Item Number
H335360
Grouped product items
SKUSizeAvailabilityPrice Qty
H335360-2.5mg
2.5mg
Available within 8-12 weeks(?)
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$332.90

a nonpeptide AT1 receptor antagonist

Basic Description

Synonyms188259-69-0|Valeryl-4-hydroxyvalsartan|4-hydroxy valsartan|4-Hydroxyvalsartan|N891C54AXX|CGP-71580|UNII-N891C54AXX|(2S)-2-[4-hydroxypentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]-3-methylbutanoic acid|L-Valine, N-(4-hydroxy-1-oxopentyl)-N-
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

4-Hydroxy Valsartan (Mixture of Diastereomers) is a nonpeptide angiotensin II AT1-receptor antagonist. Blocking the action of angiotensin II prevents vasoconstriction and in turn allows for larger capillary blood volume.

Names and Identifiers

IUPAC Name (2S)-2-[4-hydroxypentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]-3-methylbutanoic acid
INCHI InChI=1S/C24H29N5O4/c1-15(2)22(24(32)33)29(21(31)13-8-16(3)30)14-17-9-11-18(12-10-17)19-6-4-5-7-20(19)23-25-27-28-26-23/h4-7,9-12,15-16,22,30H,8,13-14H2,1-3H3,(H,32,33)(H,25,26,27,28)/t16?,22-/m0/s1
InChi Key ICSQZMPILLPFKC-XLDIYJRPSA-N
Canonical SMILES CC(C)C(C(=O)O)N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=NNN=N3)C(=O)CCC(C)O
Isomeric SMILES CC(C)[C@@H](C(=O)O)N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=NNN=N3)C(=O)CCC(C)O
PubChem CID 9911647
Molecular Weight 451.52

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySoluble in Ethanol and Methanol
Melt Point(°C)94-98° C

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Solution Calculators