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4-Hydroxy Valsartan (Mixture of Diastereomers) , CAS No.188259-69-0
a nonpeptide AT1 receptor antagonist
Basic Description Synonyms CHEBI:165851 | ICSQZMPILLPFKC-XLDIYJRPSA-N | AKOS040754785 | Valeryl-4-hydroxyvalsartan | Q27284701 | SCHEMBL3473667 | PD120067 | L-Valine, N-(4-hydroxy-1-oxopentyl)-N-((2'-(2H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)- | N891C54AXX | L-Valine, N-(4-hydr Storage Temp Store at -20°C Shipped In Ice chest + Ice pads Product Description 4-Hydroxy Valsartan (Mixture of Diastereomers) is a nonpeptide angiotensin II AT1-receptor antagonist. Blocking the action of angiotensin II prevents vasoconstriction and in turn allows for larger capillary blood volume.
Names and Identifiers IUPAC Name (2S)-2-[4-hydroxypentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]-3-methylbutanoic acid INCHI InChI=1S/C24H29N5O4/c1-15(2)22(24(32)33)29(21(31)13-8-16(3)30)14-17-9-11-18(12-10-17)19-6-4-5-7-20(19)23-25-27-28-26-23/h4-7,9-12,15-16,22,30H,8,13-14H2,1-3H3,(H,32,33)(H,25,26,27,28)/t16?,22-/m0/s1 InChi Key ICSQZMPILLPFKC-XLDIYJRPSA-N Canonical SMILES CC(C)C(C(=O)O)N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=NNN=N3)C(=O)CCC(C)O Isomeric SMILES CC(C)[C@@H](C(=O)O)N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=NNN=N3)C(=O)CCC(C)O PubChem CID 9911647 Molecular Weight 451.52
Chemical and Physical Properties Solubility Soluble in Ethanol and Methanol Melt Point(°C) 94-98° C
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