Grouped product items

SKU

Size

Availability

Price

Qty

M158850-1ml

1ml

Available within 4-8 weeks(?)

$10.90

M158850-5ml

5ml

Available within 4-8 weeks(?)

$41.90

M158850-25ml

25ml

Available within 4-8 weeks(?)

$131.90

Basic Description

Synonyms	4-Methylcyclohexylamine\|Trans-4-Methylcyclohexylamine\|2523-55-9\|6321-23-9\|4-Methylcyclohexanamine\|2523-56-0\|trans-4-Methylcyclohexanamine\|cis-4-Methylcyclohexylamine\|Cis-4-Methylcyclohexanamine\|Cyclohexanamine, 4-methyl-\|4-methylcyclohexan-1-amine\|CIS-4-M
Specifications & Purity	99%
Storage Temp	Argon charged
Shipped In	Normal
Product Description	Product Describtion: Trans-4-methylcyclohexylamine is a spermidine synthase inhibitor

Names and Identifiers

IUPAC Name	4-methylcyclohexan-1-amine
INCHI	InChI=1S/C7H15N/c1-6-2-4-7(8)5-3-6/h6-7H,2-5,8H2,1H3
InChi Key	KSMVBYPXNKCPAJ-UHFFFAOYSA-N
Canonical SMILES	CC1CCC(CC1)N
Isomeric SMILES	CC1CCC(CC1)N
WGK Germany	3
PubChem CID	80604
Molecular Weight	113.2
Beilstein	12(4)112
Reaxy-Rn	635741

Certificates

Certificate of Analysis(COA)

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To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

3 results found

Lot Number	Certificate Type	Date	Item
K2321413	Certificate of Analysis	Nov 02, 2023	M158850
K2321435	Certificate of Analysis	Nov 02, 2023	M158850
K2321436	Certificate of Analysis	Nov 02, 2023	M158850

Chemical and Physical Properties

Sensitivity	Air Sensitive
Refractive Index	1.45
Flash Point(°F)	80.6 °F
Flash Point(°C)	27°C(lit.)
Boil Point(°C)	152°C(lit.)

Safety and Hazards(GHS)

Pictogram(s)	GHS05, GHS02
Signal	Danger
Hazard Statements	H314:Causes severe skin burns and eye damage H226:Flammable liquid and vapor
Precautionary Statements	P280:Wear protective gloves/protective clothing/eye protection/face protection. P370+P378:In case of fire: Use ... to extinguish. P210:Keep away from heat, hot surface, sparks, open flames and other ignition sources. - No smoking. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P264:Wash hands [and …] thoroughly after handling. P403+P235:Store in a well-ventilated place. Keep cool. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P303+P361+P353:IF ON SKIN (or hair): Take off Immediately all contaminated clothing. Rinse SKIN with water [or shower]. P241:Use explosion-proof [electrical/ventilating/lighting/.../] equipment. P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P363:Wash contaminated clothing before reuse. P242:Use only non-sparking tools. P243:Take precautionary measures against static discharge. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P302+P361+P354:IF ON SKIN: Take off Immediately all contaminated clothing. Immediately rinse with water for several minutes. P316:Get emergency medical help immediately.
WGK Germany	3
Reaxy-Rn	635741

References

1. T Beppu,A Shirahata,N Takahashi,H Hosoda,K Samejima. (1995-02-01) Specific depletion of spermidine and spermine in HTC cells treated with inhibitors of aminopropyltransferases.. Journal of biochemistry, 117 ((2)): (339-345). [PMID:7608122]
2. A Shirahata,N Takahashi,T Beppu,H Hosoda,K Samejima. (1993-05-05) Effects of inhibitors of spermidine synthase and spermine synthase on polyamine synthesis in rat tissues.. Biochemical pharmacology, 45 ((9)): (1897-1903). [PMID:8494549]
3. Masaki Kobayashi,Koichi Takao,Yasuo Shiota,Yoshiaki Sugita,Masakazu Takahashi,Dai Nakae,Keijiro Samejima. (2006-05-03) Inhibition of putrescine aminopropyltransferase influences rat liver regeneration.. Biological & pharmaceutical bulletin, 29 ((5)): (863-867). [PMID:16651710]
4. Keijiro Samejima. (2006-08-02) [Regulation of polyamine and cancer].. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 126 ((8)): (529-542). [PMID:16880714]
5. Masatake Sano,Ikuko Nishino. (2006-08-26) Assay for spermidine synthase activity by micellar electrokinetic chromatography with laser-induced fluorescence detection.. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 845 ((1)): (80-83). [PMID:16931179]
6. Micael Jacobsson,Magnus Gäredal,Johan Schultz,Anders Karlén. (2008-04-16) Identification of Plasmodium falciparum spermidine synthase active site binders through structure-based virtual screening.. Journal of medicinal chemistry, 51 ((9)): (2777-2786). [PMID:18410081]
7. TachaZi Plym Forshell,Sara Rimpi,Jonas A Nilsson. (2010-01-28) Chemoprevention of B-cell lymphomas by inhibition of the Myc target spermidine synthase.. Cancer prevention research (Philadelphia, Pa.), 3 ((2)): (140-147). [PMID:20103729]
8. Ikumi Ishii,Yoshihiko Ikeguchi,Hiroshi Mano,Masahiro Wada,Anthony E Pegg,Akira Shirahata. (2011-08-03) Polyamine metabolism is involved in adipogenesis of 3T3-L1 cells.. Amino acids, 42 ((2-3)): (619-626). [PMID:21809076]
9. A Shirahata,T Morohoshi,K Samejima. (1988-08-01) Trans-4-methylcyclohexylamine, a potent new inhibitor of spermidine synthase.. Chemical & pharmaceutical bulletin, 36 ((8)): (3220-3222). [PMID:3240528]
10. Y He,T Shimogori,K Kashiwagi,A Shirahata,K Igarashi. (1995-04-01) Inhibition of cell growth by combination of alpha-difluoromethylornithine and an inhibitor of spermine synthase.. Journal of biochemistry, 117 ((4)): (824-829). [PMID:7592545]
11. Hitomi Goda,Toshiko Watanabe,Noboru Takeda,Masaki Kobayashi,Makiko Wada,Harumi Hosoda,Akira Shirahata,Keijiro Samejima. (2004-09-02) Mammalian spermidine synthase--identification of cysteine residues and investigation of the putrescine binding site--.. Biological & pharmaceutical bulletin, 27 ((9)): (1327-1332). [PMID:15340214]
12. Masaki Kobayashi,Toshiko Watanabe,Yong Ji Xu,Minoru Tatemori,Hitomi Goda,Masaru Niitsu,Akira Shirahata,Keijiro Samejima. (2005-04-02) Control of spermidine and spermine levels in rat tissues by trans-4-methylcyclohexylamine, a spermidine-synthase inhibitor.. Biological & pharmaceutical bulletin, 28 ((4)): (569-573). [PMID:15802788]
13. Keijiro Samejima,Masahiro Otani,Yasuko Murakami,Takami Oka,Misao Kasai,Hiroki Tsumoto,Kohfuku Kohda. (2007-10-06) Electrospray ionization and time-of-flight mass spectrometric method for simultaneous determination of spermidine and spermine.. Biological & pharmaceutical bulletin, 30 ((10)): (1943-1946). [PMID:17917267]
14. Masahiro Ohtani,Ikuko Mizuno,Yumiko Kojima,Yuichi Ishikawa,Midori Sodeno,Yuka Asakura,Keijiro Samejima,Takami Oka. (2009-10-31) Spermidine regulates insulin synthesis and cytoplasmic Ca(2+) in mouse beta-TC6 insulinoma cells.. Cell structure and function, 34 ((2)): (105-113). [PMID:19875898]

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4-Methylcyclohexylamine (cis- and trans- mixture) - 99%, high purity , CAS No.6321-23-9

Basic Description

Names and Identifiers

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

Safety and Hazards(GHS)

Related Documents

References

Solution Calculators

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

SKU	Size	Availability	Price
M158850-1ml	1ml	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$10.90
M158850-5ml	5ml	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$41.90
M158850-25ml	25ml	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$131.90